Routine use of gradient-echo MRI to screen for cerebral amyloid angiopathy in elderly patients

D. A. Walker, D. F. Broderick, A. L. Kotsenas, F. A. Rubino

Research output: Contribution to journalArticle

50 Scopus citations


OBJECTIVE. The objective of this study was to evaluate the routine use of gradient-refocused echo MRI sequences in the detection of cortical cerebral microbleeding suggestive of cerebral amyloid angiopathy in elderly patients (> 70 years old). CONCLUSION. The addition of gradient-refocused echo sequences to routine brain MRI resulted in the identification of cerebral amyloid angiopathy-related microbleeding in 15.5% of elderly patients. In most (86.7%) of these patients with positive findings, cerebral amyloid angiopathy was not suspected clinically, and 46.7% of these patients were undergoing anticoagulant or aspirin therapy, placing them at an increased risk of recurrent intracranial hemorrhage and catastrophic stroke.

Original languageEnglish (US)
Pages (from-to)1547-1550
Number of pages4
JournalAmerican Journal of Roentgenology
Issue number6
StatePublished - Jun 2004


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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