Routine use of gradient-echo MRI to screen for cerebral amyloid angiopathy in elderly patients

D. A. Walker, D. F. Broderick, A. L. Kotsenas, F. A. Rubino

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

OBJECTIVE. The objective of this study was to evaluate the routine use of gradient-refocused echo MRI sequences in the detection of cortical cerebral microbleeding suggestive of cerebral amyloid angiopathy in elderly patients (> 70 years old). CONCLUSION. The addition of gradient-refocused echo sequences to routine brain MRI resulted in the identification of cerebral amyloid angiopathy-related microbleeding in 15.5% of elderly patients. In most (86.7%) of these patients with positive findings, cerebral amyloid angiopathy was not suspected clinically, and 46.7% of these patients were undergoing anticoagulant or aspirin therapy, placing them at an increased risk of recurrent intracranial hemorrhage and catastrophic stroke.

Original languageEnglish (US)
Pages (from-to)1547-1550
Number of pages4
JournalAmerican Journal of Roentgenology
Volume182
Issue number6
StatePublished - Jun 2004

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Cerebral Amyloid Angiopathy
Intracranial Hemorrhages
Anticoagulants
Aspirin
Stroke
Brain

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Walker, D. A., Broderick, D. F., Kotsenas, A. L., & Rubino, F. A. (2004). Routine use of gradient-echo MRI to screen for cerebral amyloid angiopathy in elderly patients. American Journal of Roentgenology, 182(6), 1547-1550.

Routine use of gradient-echo MRI to screen for cerebral amyloid angiopathy in elderly patients. / Walker, D. A.; Broderick, D. F.; Kotsenas, A. L.; Rubino, F. A.

In: American Journal of Roentgenology, Vol. 182, No. 6, 06.2004, p. 1547-1550.

Research output: Contribution to journalArticle

Walker, DA, Broderick, DF, Kotsenas, AL & Rubino, FA 2004, 'Routine use of gradient-echo MRI to screen for cerebral amyloid angiopathy in elderly patients', American Journal of Roentgenology, vol. 182, no. 6, pp. 1547-1550.
Walker, D. A. ; Broderick, D. F. ; Kotsenas, A. L. ; Rubino, F. A. / Routine use of gradient-echo MRI to screen for cerebral amyloid angiopathy in elderly patients. In: American Journal of Roentgenology. 2004 ; Vol. 182, No. 6. pp. 1547-1550.
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