Rosai-dorfman disease: Manifestations outside of the head and neck

Winnie A. Mar, H. Yu Jonathan, Grace Knuttinen, Jeanne M. Horowitz, Odile David, Andrew Wilbur, Christine O. Menias

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

OBJECTIVE. Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION. The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.

Original languageEnglish (US)
Pages (from-to)721-732
Number of pages12
JournalAmerican Journal of Roentgenology
Volume208
Issue number4
DOIs
StatePublished - Apr 1 2017

Keywords

  • Abdominal
  • Extranodal
  • Histiocytosis
  • Rosai-Dorfman disease
  • Thoracic

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Mar, W. A., Jonathan, H. Y., Knuttinen, G., Horowitz, J. M., David, O., Wilbur, A., & Menias, C. O. (2017). Rosai-dorfman disease: Manifestations outside of the head and neck. American Journal of Roentgenology, 208(4), 721-732. https://doi.org/10.2214/AJR.15.15504