Rosai-dorfman disease: Manifestations outside of the head and neck

Winnie A. Mar; H. Yu Jonathan; Martha Gracia Knuttinen; Jeanne M. Horowitz; Odile David; Andrew Wilbur; Christine O. Menias

doi:10.2214/AJR.15.15504

Rosai-dorfman disease: Manifestations outside of the head and neck

Winnie A. Mar, H. Yu Jonathan, Martha Gracia Knuttinen, Jeanne M. Horowitz, Odile David, Andrew Wilbur, Christine O. Menias

Diagnostic Radiology

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

OBJECTIVE. Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION. The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.

Original language	English (US)
Pages (from-to)	721-732
Number of pages	12
Journal	American Journal of Roentgenology
Volume	208
Issue number	4
DOIs	https://doi.org/10.2214/AJR.15.15504
State	Published - Apr 2017

Keywords

Abdominal
Extranodal
Histiocytosis
Rosai-Dorfman disease
Thoracic

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.2214/AJR.15.15504

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title = "Rosai-dorfman disease: Manifestations outside of the head and neck",

abstract = "OBJECTIVE. Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION. The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.",

keywords = "Abdominal, Extranodal, Histiocytosis, Rosai-Dorfman disease, Thoracic",

author = "Mar, {Winnie A.} and Jonathan, {H. Yu} and Knuttinen, {Martha Gracia} and Horowitz, {Jeanne M.} and Odile David and Andrew Wilbur and Menias, {Christine O.}",

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year = "2017",

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T2 - Manifestations outside of the head and neck

AU - Mar, Winnie A.

AU - Jonathan, H. Yu

AU - Knuttinen, Martha Gracia

AU - Horowitz, Jeanne M.

AU - David, Odile

AU - Wilbur, Andrew

AU - Menias, Christine O.

N1 - Publisher Copyright: © American Roentgen Ray Society.

PY - 2017/4

Y1 - 2017/4

N2 - OBJECTIVE. Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION. The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.

AB - OBJECTIVE. Rosai-Dorfman disease (RDD) is an uncommon benign histiocytic disorder. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. We review less common imaging findings outside the head and neck. CONCLUSION. The imaging manifestations of RDD overlap with a variety of neoplastic and nonneoplastic conditions. Confirmation of an RDD diagnosis is based on specific histologic features. Radiologic assessment is used to rule out multifocality on initial workup and to evaluate treatment response.

KW - Abdominal

KW - Extranodal

KW - Histiocytosis

KW - Rosai-Dorfman disease

KW - Thoracic

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Rosai-dorfman disease: Manifestations outside of the head and neck

Abstract

Keywords

ASJC Scopus subject areas

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