Role of ischemic preconditioning in liver surgery and hepatic transplantation

Eduardo E. Montalvo-Jave, Enrique Piña, Cesar Montalvo-Arenas, Raúl Urrutia, Luis Benavente-Chenhalls, Julieta Peña-Sanchez, David A. Geller

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Introduction The purpose of this review is to summarize intraoperative surgical strategies available to decrease ischemiareperfusion injury associated with liver resection and liver transplantation. Material and method We conducted a critical review of the literature evaluating the potential applications of hepatic ischemic preconditioning (IPC) for hepatic resection surgery and liver transplantation. In addition, we provide a basic bench-to-bedside summary of the liver physiology and cell signaling mechanisms that account for the protective effects seen with hepatic IPC.

Original languageEnglish (US)
Pages (from-to)2074-2083
Number of pages10
JournalJournal of Gastrointestinal Surgery
Volume13
Issue number11
DOIs
StatePublished - 2009

Keywords

  • Liver. Ischemia-reperfusion injury. Hepatic transplantation. Preconditioning. Surgery. Ischemic preconditioning

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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