Rhabdomyolysis and myoglobinuric acute renal failure associated with classic heat stroke

Winston Tan, B. C. Herzlich, R. Funaro, K. Koutelos, M. Pagala, B. Amaladevi, D. Grob

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Classic heat stroke is a disorder of thermal regulation that predominantly affects elderly patients during heat waves. In contrast to exertional heat stroke, rhabdomyolysis and myoglobinuric acute renal failure are considered to be unusual manifestations of classic heat stroke. We retrospectively reviewed the charts of seven patients admitted to Maimonides Medical Center with classic heat stroke over a 3-day period during a heat wave in July 1993. Three of these patients with classic heat stroke had rhabdomyolysis, but no renal failure; two completely recovered; and one had an ataxic gait disturbance. Three additional patients had rhabdomyolysis and myoglobinuric acute renal failure; one of them completely recovered, one survived with quadriplegia, and one died. Our findings suggest that rhabdomyolysis and myoglobinuric acute renal failure are common manifestations of classic heat stroke. Recognition of this complication warrants rigorous hydration and alkalinization of the urine to prevent or attenuate myoglobinuric acute renal failure.

Original languageEnglish (US)
Pages (from-to)1065-1068
Number of pages4
JournalSouthern Medical Journal
Volume88
Issue number10
StatePublished - 1995
Externally publishedYes

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Heat Stroke
Rhabdomyolysis
Acute Kidney Injury
Infrared Rays
Quadriplegia
Gait
Renal Insufficiency
Hot Temperature
Urine

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tan, W., Herzlich, B. C., Funaro, R., Koutelos, K., Pagala, M., Amaladevi, B., & Grob, D. (1995). Rhabdomyolysis and myoglobinuric acute renal failure associated with classic heat stroke. Southern Medical Journal, 88(10), 1065-1068.

Rhabdomyolysis and myoglobinuric acute renal failure associated with classic heat stroke. / Tan, Winston; Herzlich, B. C.; Funaro, R.; Koutelos, K.; Pagala, M.; Amaladevi, B.; Grob, D.

In: Southern Medical Journal, Vol. 88, No. 10, 1995, p. 1065-1068.

Research output: Contribution to journalArticle

Tan, W, Herzlich, BC, Funaro, R, Koutelos, K, Pagala, M, Amaladevi, B & Grob, D 1995, 'Rhabdomyolysis and myoglobinuric acute renal failure associated with classic heat stroke', Southern Medical Journal, vol. 88, no. 10, pp. 1065-1068.
Tan W, Herzlich BC, Funaro R, Koutelos K, Pagala M, Amaladevi B et al. Rhabdomyolysis and myoglobinuric acute renal failure associated with classic heat stroke. Southern Medical Journal. 1995;88(10):1065-1068.
Tan, Winston ; Herzlich, B. C. ; Funaro, R. ; Koutelos, K. ; Pagala, M. ; Amaladevi, B. ; Grob, D. / Rhabdomyolysis and myoglobinuric acute renal failure associated with classic heat stroke. In: Southern Medical Journal. 1995 ; Vol. 88, No. 10. pp. 1065-1068.
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