Resurgence of Eating Disorders with Olanzapine

Kelly L. Wu; Amanda K. Lorenz; Kelly J. Christensen; Molly A. Feely; Elise C. Carey; Jacob J. Strand

doi:10.1089/jpm.2018.0364

Resurgence of Eating Disorders with Olanzapine

Kelly L. Wu, Amanda K. Lorenz, Kelly J. Christensen, Molly A. Feely, Elise C. Carey, Jacob J. Strand

General Internal Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Background: Olanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness. Methods and Results: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine. Conclusion: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.

Original language	English (US)
Pages (from-to)	231-233
Number of pages	3
Journal	Journal of Palliative Medicine
Volume	22
Issue number	2
DOIs	https://doi.org/10.1089/jpm.2018.0364
State	Published - Feb 2019

Keywords

feeding and eating disorders
nausea
palliative

ASJC Scopus subject areas

General Nursing
Anesthesiology and Pain Medicine

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10.1089/jpm.2018.0364

Cite this

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title = "Resurgence of Eating Disorders with Olanzapine",

abstract = "Background: Olanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness. Methods and Results: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine. Conclusion: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.",

keywords = "feeding and eating disorders, nausea, palliative",

author = "Wu, {Kelly L.} and Lorenz, {Amanda K.} and Christensen, {Kelly J.} and Feely, {Molly A.} and Carey, {Elise C.} and Strand, {Jacob J.}",

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doi = "10.1089/jpm.2018.0364",

language = "English (US)",

volume = "22",

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journal = "Journal of Palliative Medicine",

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T1 - Resurgence of Eating Disorders with Olanzapine

AU - Wu, Kelly L.

AU - Lorenz, Amanda K.

AU - Christensen, Kelly J.

AU - Feely, Molly A.

AU - Carey, Elise C.

AU - Strand, Jacob J.

PY - 2019/2

Y1 - 2019/2

N2 - Background: Olanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness. Methods and Results: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine. Conclusion: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.

AB - Background: Olanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness. Methods and Results: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine. Conclusion: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.

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KW - nausea

KW - palliative

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Resurgence of Eating Disorders with Olanzapine

Abstract

Keywords

ASJC Scopus subject areas

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