Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health

Richard P. Allen; Daniel Picchietti; Wayne A. Hening; Claudia Trenkwalder; Arthur S. Walters; Jacques Montplaisi; William Bara-Jimenez; Philip Becker; Georgianna Bell; Klaus Berger; Donald L. Bliwise; David Brooks; Flavia Consens; Christopher J. Earley; Bruce L. Ehrenberg; Daniel Foley; Catherine Friederich Murray; Diego Garcia-Borreguero; Mark Hallett; Magdolna Hornyak; Carl E. Hunt; Clete Kushida; Tobias Kurth; Lenore Launer; Andrew Monjan; Paul Nichols; David B. Rye; Denise Sharon; David L. Streiner; John W. Winkelman; Juliane Winkelmann; Rochelle Zak; Charles Adler; Heike Benes; Sudhansu Chokroverty; Karl Ekbom; Birgit Frauscher; Birgit Högl; Meir Kryger; Pasquale Montagna; Wolfgang Oertel; Giuseppe Plazzi; J. Steven Poceta; Michael Silber; Karin Stiasny; Eduardo Tolosa; Sergio Tufik; Marco Tulio de Mello; Marco Zucconi

doi:10.1016/S1389-9457(03)00010-8

Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health

Richard P. Allen, Daniel Picchietti, Wayne A. Hening, Claudia Trenkwalder, Arthur S. Walters, Jacques Montplaisi, William Bara-Jimenez, Philip Becker, Georgianna Bell, Klaus Berger, Donald L. Bliwise, David Brooks, Flavia Consens, Christopher J. Earley, Bruce L. Ehrenberg, Daniel Foley, Catherine Friederich Murray, Diego Garcia-Borreguero, Mark Hallett, Magdolna HornyakCarl E. Hunt, Clete Kushida, Tobias Kurth, Lenore Launer, Andrew Monjan, Paul Nichols, David B. Rye, Denise Sharon, David L. Streiner, John W. Winkelman, Juliane Winkelmann, Rochelle Zak, Charles Adler, Heike Benes, Sudhansu Chokroverty, Karl Ekbom, Birgit Frauscher, Birgit Högl, Meir Kryger, Pasquale Montagna, Wolfgang Oertel, Giuseppe Plazzi, J. Steven Poceta, Michael Silber, Karin Stiasny, Eduardo Tolosa, Sergio Tufik, Marco Tulio de Mello, Marco Zucconi

Neurology

Research output: Contribution to journal › Article › peer-review

2412 Scopus citations

Abstract

Background: Restless legs syndrome is a common yet frequently undiagnosed sensorimotor disorder. In 1995, the International Restless Legs Syndrome Study Group developed standardized criteria for the diagnosis of restless legs syndrome. Since that time, additional scientific scrutiny and clinical experience have led to a better understanding of the condition. Modification of the criteria is now necessary to better reflect that increased body of knowledge, as well as to clarify slight confusion with the wording of the original criteria. Setting: The restless legs syndrome diagnostic criteria and epidemiology workshop at the National Institutes of Health. Participants: Members of the International Restless Legs Syndrome Study Group and authorities on epidemiology and the design of questionnaires and scales. Objective: To modify the current criteria for the diagnosis of restless legs syndrome, to develop new criteria for the diagnosis of restless legs syndrome in the cognitively impaired elderly and in children, to create standardized criteria for the identification of augmentation, and to establish consistent questions for use in epidemiology studies. Results: The essential diagnostic criteria for restless legs syndrome were developed and approved by workshop participants and the executive committee of the International Restless Legs Syndrome Study Group. Criteria were also developed and approved for the additional aforementioned groups.

Original language	English (US)
Pages (from-to)	101-119
Number of pages	19
Journal	Sleep Medicine
Volume	4
Issue number	2
DOIs	https://doi.org/10.1016/S1389-9457(03)00010-8
State	Published - Mar 2003

Keywords

Consensus
Movement disorder
Neurologic disorder
Periodic limb movement disorder
Periodic limb movements of sleep
Sleep
Sleep disorder

ASJC Scopus subject areas

General Medicine

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10.1016/S1389-9457(03)00010-8

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Allen, R. P., Picchietti, D., Hening, W. A., Trenkwalder, C., Walters, A. S., Montplaisi, J., Bara-Jimenez, W., Becker, P., Bell, G., Berger, K., Bliwise, D. L., Brooks, D., Consens, F., Earley, C. J., Ehrenberg, B. L., Foley, D., Murray, C. F., Garcia-Borreguero, D., Hallett, M., ... Zucconi, M. (2003). Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Medicine, 4(2), 101-119. https://doi.org/10.1016/S1389-9457(03)00010-8

Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. / Allen, Richard P.; Picchietti, Daniel; Hening, Wayne A. et al.
In: Sleep Medicine, Vol. 4, No. 2, 03.2003, p. 101-119.

Research output: Contribution to journal › Article › peer-review

Allen, RP, Picchietti, D, Hening, WA, Trenkwalder, C, Walters, AS, Montplaisi, J, Bara-Jimenez, W, Becker, P, Bell, G, Berger, K, Bliwise, DL, Brooks, D, Consens, F, Earley, CJ, Ehrenberg, BL, Foley, D, Murray, CF, Garcia-Borreguero, D, Hallett, M, Hornyak, M, Hunt, CE, Kushida, C, Kurth, T, Launer, L, Monjan, A, Nichols, P, Rye, DB, Sharon, D, Streiner, DL, Winkelman, JW, Winkelmann, J, Zak, R, Adler, C, Benes, H, Chokroverty, S, Ekbom, K, Frauscher, B, Högl, B, Kryger, M, Montagna, P, Oertel, W, Plazzi, G, Poceta, JS, Silber, M, Stiasny, K, Tolosa, E, Tufik, S, de Mello, MT & Zucconi, M 2003, 'Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health', Sleep Medicine, vol. 4, no. 2, pp. 101-119. https://doi.org/10.1016/S1389-9457(03)00010-8

@article{ecfc6b62ac0f4b1db83d1c4edb865268,

title = "Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health",

abstract = "Background: Restless legs syndrome is a common yet frequently undiagnosed sensorimotor disorder. In 1995, the International Restless Legs Syndrome Study Group developed standardized criteria for the diagnosis of restless legs syndrome. Since that time, additional scientific scrutiny and clinical experience have led to a better understanding of the condition. Modification of the criteria is now necessary to better reflect that increased body of knowledge, as well as to clarify slight confusion with the wording of the original criteria. Setting: The restless legs syndrome diagnostic criteria and epidemiology workshop at the National Institutes of Health. Participants: Members of the International Restless Legs Syndrome Study Group and authorities on epidemiology and the design of questionnaires and scales. Objective: To modify the current criteria for the diagnosis of restless legs syndrome, to develop new criteria for the diagnosis of restless legs syndrome in the cognitively impaired elderly and in children, to create standardized criteria for the identification of augmentation, and to establish consistent questions for use in epidemiology studies. Results: The essential diagnostic criteria for restless legs syndrome were developed and approved by workshop participants and the executive committee of the International Restless Legs Syndrome Study Group. Criteria were also developed and approved for the additional aforementioned groups.",

keywords = "Consensus, Movement disorder, Neurologic disorder, Periodic limb movement disorder, Periodic limb movements of sleep, Sleep, Sleep disorder",

author = "Allen, {Richard P.} and Daniel Picchietti and Hening, {Wayne A.} and Claudia Trenkwalder and Walters, {Arthur S.} and Jacques Montplaisi and William Bara-Jimenez and Philip Becker and Georgianna Bell and Klaus Berger and Bliwise, {Donald L.} and David Brooks and Flavia Consens and Earley, {Christopher J.} and Ehrenberg, {Bruce L.} and Daniel Foley and Murray, {Catherine Friederich} and Diego Garcia-Borreguero and Mark Hallett and Magdolna Hornyak and Hunt, {Carl E.} and Clete Kushida and Tobias Kurth and Lenore Launer and Andrew Monjan and Paul Nichols and Rye, {David B.} and Denise Sharon and Streiner, {David L.} and Winkelman, {John W.} and Juliane Winkelmann and Rochelle Zak and Charles Adler and Heike Benes and Sudhansu Chokroverty and Karl Ekbom and Birgit Frauscher and Birgit H{\"o}gl and Meir Kryger and Pasquale Montagna and Wolfgang Oertel and Giuseppe Plazzi and Poceta, {J. Steven} and Michael Silber and Karin Stiasny and Eduardo Tolosa and Sergio Tufik and {de Mello}, {Marco Tulio} and Marco Zucconi",

note = "Funding Information: We wish to thank Pharmacia Corporation for their generous unrestricted grant to the Restless Legs Syndrome Foundation to provide part of the support for this workshop and the staff of the National Institute on Aging and the National Center on Sleep Disorders Research for their help in planning and conducting this workshop. We wish to thank the Restless Legs Syndrome Foundation for their efforts in organizing this workshop and to the RLS Foundation staff, particularly the Executive Director, Georgianna Bell, for the time and effort spent on organizing the workshop and supporting production of this workshop report. We wish to especially thank Catherine Friederich Murray for her expert technical writing and organizational skills that were essential for the completion of this report. Her exceptional professional skills, ready availability, and persistence served to ensure quality, thoroughness and completion of the manuscript. We wish to acknowledge that the following employees of pharmaceutical companies attended the workshop and many of them made very helpful contributions to the deliberations: Mark Atkinson, PhD, Pharmacia Corporation, Kalamazoo, MI; Trevor J. Brown, Premark Services Ltd, Crawley Down, West Sussex, UK; Janeen DuChane, PhD, Pharmacia Corporation, Kalamazoo, MI; Nancy Earl, MD, GlaxoSmithKline, Research Triangle Park, NC; Susan Hogan, PhD, MNS, Embryon Inc., Somerville, NJ; Norinder Lotay, GlaxoSmithKline, Research Triangle Park, NC; Eileen T. Monaghan, GlaxoSmithKline, Research Triangle Park, NC; Bruno Musch, MD, Pharmacia Corporation, Peapack, NJ; Kevin Pawley, Medical Education Systems, Inc., San Diego, CA; Kenneth, A, Selzer, MD, Pharmacia Corporation, Peapack, NJ; C. Eugene Wright, Pharmacia Corporation, Peapack, NJ. ",

year = "2003",

month = mar,

doi = "10.1016/S1389-9457(03)00010-8",

language = "English (US)",

volume = "4",

pages = "101--119",

journal = "Sleep Medicine",

issn = "1389-9457",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - Restless legs syndrome

T2 - Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health

AU - Allen, Richard P.

AU - Picchietti, Daniel

AU - Hening, Wayne A.

AU - Trenkwalder, Claudia

AU - Walters, Arthur S.

AU - Montplaisi, Jacques

AU - Bara-Jimenez, William

AU - Becker, Philip

AU - Bell, Georgianna

AU - Berger, Klaus

AU - Bliwise, Donald L.

AU - Brooks, David

AU - Consens, Flavia

AU - Earley, Christopher J.

AU - Ehrenberg, Bruce L.

AU - Foley, Daniel

AU - Murray, Catherine Friederich

AU - Garcia-Borreguero, Diego

AU - Hallett, Mark

AU - Hornyak, Magdolna

AU - Hunt, Carl E.

AU - Kushida, Clete

AU - Kurth, Tobias

AU - Launer, Lenore

AU - Monjan, Andrew

AU - Nichols, Paul

AU - Rye, David B.

AU - Sharon, Denise

AU - Streiner, David L.

AU - Winkelman, John W.

AU - Winkelmann, Juliane

AU - Zak, Rochelle

AU - Adler, Charles

AU - Benes, Heike

AU - Chokroverty, Sudhansu

AU - Ekbom, Karl

AU - Frauscher, Birgit

AU - Högl, Birgit

AU - Kryger, Meir

AU - Montagna, Pasquale

AU - Oertel, Wolfgang

AU - Plazzi, Giuseppe

AU - Poceta, J. Steven

AU - Silber, Michael

AU - Stiasny, Karin

AU - Tolosa, Eduardo

AU - Tufik, Sergio

AU - de Mello, Marco Tulio

AU - Zucconi, Marco

N1 - Funding Information: We wish to thank Pharmacia Corporation for their generous unrestricted grant to the Restless Legs Syndrome Foundation to provide part of the support for this workshop and the staff of the National Institute on Aging and the National Center on Sleep Disorders Research for their help in planning and conducting this workshop. We wish to thank the Restless Legs Syndrome Foundation for their efforts in organizing this workshop and to the RLS Foundation staff, particularly the Executive Director, Georgianna Bell, for the time and effort spent on organizing the workshop and supporting production of this workshop report. We wish to especially thank Catherine Friederich Murray for her expert technical writing and organizational skills that were essential for the completion of this report. Her exceptional professional skills, ready availability, and persistence served to ensure quality, thoroughness and completion of the manuscript. We wish to acknowledge that the following employees of pharmaceutical companies attended the workshop and many of them made very helpful contributions to the deliberations: Mark Atkinson, PhD, Pharmacia Corporation, Kalamazoo, MI; Trevor J. Brown, Premark Services Ltd, Crawley Down, West Sussex, UK; Janeen DuChane, PhD, Pharmacia Corporation, Kalamazoo, MI; Nancy Earl, MD, GlaxoSmithKline, Research Triangle Park, NC; Susan Hogan, PhD, MNS, Embryon Inc., Somerville, NJ; Norinder Lotay, GlaxoSmithKline, Research Triangle Park, NC; Eileen T. Monaghan, GlaxoSmithKline, Research Triangle Park, NC; Bruno Musch, MD, Pharmacia Corporation, Peapack, NJ; Kevin Pawley, Medical Education Systems, Inc., San Diego, CA; Kenneth, A, Selzer, MD, Pharmacia Corporation, Peapack, NJ; C. Eugene Wright, Pharmacia Corporation, Peapack, NJ.

PY - 2003/3

Y1 - 2003/3

N2 - Background: Restless legs syndrome is a common yet frequently undiagnosed sensorimotor disorder. In 1995, the International Restless Legs Syndrome Study Group developed standardized criteria for the diagnosis of restless legs syndrome. Since that time, additional scientific scrutiny and clinical experience have led to a better understanding of the condition. Modification of the criteria is now necessary to better reflect that increased body of knowledge, as well as to clarify slight confusion with the wording of the original criteria. Setting: The restless legs syndrome diagnostic criteria and epidemiology workshop at the National Institutes of Health. Participants: Members of the International Restless Legs Syndrome Study Group and authorities on epidemiology and the design of questionnaires and scales. Objective: To modify the current criteria for the diagnosis of restless legs syndrome, to develop new criteria for the diagnosis of restless legs syndrome in the cognitively impaired elderly and in children, to create standardized criteria for the identification of augmentation, and to establish consistent questions for use in epidemiology studies. Results: The essential diagnostic criteria for restless legs syndrome were developed and approved by workshop participants and the executive committee of the International Restless Legs Syndrome Study Group. Criteria were also developed and approved for the additional aforementioned groups.

AB - Background: Restless legs syndrome is a common yet frequently undiagnosed sensorimotor disorder. In 1995, the International Restless Legs Syndrome Study Group developed standardized criteria for the diagnosis of restless legs syndrome. Since that time, additional scientific scrutiny and clinical experience have led to a better understanding of the condition. Modification of the criteria is now necessary to better reflect that increased body of knowledge, as well as to clarify slight confusion with the wording of the original criteria. Setting: The restless legs syndrome diagnostic criteria and epidemiology workshop at the National Institutes of Health. Participants: Members of the International Restless Legs Syndrome Study Group and authorities on epidemiology and the design of questionnaires and scales. Objective: To modify the current criteria for the diagnosis of restless legs syndrome, to develop new criteria for the diagnosis of restless legs syndrome in the cognitively impaired elderly and in children, to create standardized criteria for the identification of augmentation, and to establish consistent questions for use in epidemiology studies. Results: The essential diagnostic criteria for restless legs syndrome were developed and approved by workshop participants and the executive committee of the International Restless Legs Syndrome Study Group. Criteria were also developed and approved for the additional aforementioned groups.

KW - Consensus

KW - Movement disorder

KW - Neurologic disorder

KW - Periodic limb movement disorder

KW - Periodic limb movements of sleep

KW - Sleep

KW - Sleep disorder

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C2 - 14592341

AN - SCOPUS:0037738587

SN - 1389-9457

VL - 4

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JO - Sleep Medicine

JF - Sleep Medicine

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ER -

Restless legs syndrome: Diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health

Abstract

Keywords

ASJC Scopus subject areas

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