Response to immunosuppressive therapy in patients with hereditary motor and sensory neuropathy and associated dysimmune neuromuscular disorders

G. W. Mitchell, E. P. Bosch, M. N. Hart

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

We encountered 2 patients with hereditary motor and sensory neuropathy (HMSN) type I who had marked weakness developing during several months superimposed on chronic peroneal muscular atrophy. Further studies disclosed a chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in one patient and CIDP associated with polymyositis in the other. Both patients responded to prednisone and azathioprine with substantial improvement. Patient with HMSN who develop rapid progression of weakness should be evaluated for superimposed, potentially treatable dysimmune neuromuscular disorders.

Original languageEnglish (US)
Pages (from-to)188-196
Number of pages9
JournalEuropean Neurology
Volume27
Issue number3
StatePublished - 1987
Externally publishedYes

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Hereditary Sensory and Motor Neuropathy
Immunosuppressive Agents
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Charcot-Marie-Tooth Disease
Polymyositis
Azathioprine
Therapeutics
Prednisone

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Response to immunosuppressive therapy in patients with hereditary motor and sensory neuropathy and associated dysimmune neuromuscular disorders. / Mitchell, G. W.; Bosch, E. P.; Hart, M. N.

In: European Neurology, Vol. 27, No. 3, 1987, p. 188-196.

Research output: Contribution to journalArticle

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