Renal stone epidemiology in Rochester, Minnesota: An update

J. C. Lieske, L. S. Peña De La Vega, J. M. Slezak, E. J. Bergstralh, C. L. Leibson, K. L. Ho, M. T. Gettman

Research output: Contribution to journalArticlepeer-review

167 Scopus citations


Studies in Western countries have suggested an increasing incidence of nephrolithiasis (NL) in the latter part of the 20th century. Therefore, we updated NL epidemiology data for the Rochester population over the years 1970-2000. All Rochester residents with any diagnostic code that could be linked to NL in the years of 1970, 1980, 1990, and 2000 were identified, and the records reviewed to determine if they met the criteria for a symptomatic kidney stone as defined in a previous Rochester, MN study. Age-adjusted incidence (±s.e.) of new onset symptomatic stone disease for men was 155.1 (±28.5) and 105.0 (±16.8) per 100 000 per year in 1970 and 2000, respectively. For women, the corresponding rates were 43.2 (±14.0) and 68.4 (±12.3) per 100 000 per year, respectively. On average, rates for women increased by about 1.9% per year (P = 0.064), whereas rates for men declined by 1.7% per year (P = 0.019). The overall man to woman ratio decreased from 3.1 to 1.3 during the 30 years (P = 0.006). Incident stone rates were highest for men aged 60-69 years, whereas for women, they plateaued after age 30. Therefore, since 1970 overall NL incidence rates in Rochester have remained relatively flat. However, NL rates for men have declined, whereas rates for women appear to be increasing. The reasons remain to be determined.

Original languageEnglish (US)
Pages (from-to)760-764
Number of pages5
JournalKidney international
Issue number4
StatePublished - Feb 2006


  • Calcium oxalate
  • Incidence
  • Kidney stone
  • Nephrolithiasis
  • Sex

ASJC Scopus subject areas

  • Nephrology


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