@article{9c9401c653f349a0ab438685f2982766,
title = "Renal stone epidemiology in Rochester, Minnesota: An update",
abstract = "Studies in Western countries have suggested an increasing incidence of nephrolithiasis (NL) in the latter part of the 20th century. Therefore, we updated NL epidemiology data for the Rochester population over the years 1970-2000. All Rochester residents with any diagnostic code that could be linked to NL in the years of 1970, 1980, 1990, and 2000 were identified, and the records reviewed to determine if they met the criteria for a symptomatic kidney stone as defined in a previous Rochester, MN study. Age-adjusted incidence (±s.e.) of new onset symptomatic stone disease for men was 155.1 (±28.5) and 105.0 (±16.8) per 100 000 per year in 1970 and 2000, respectively. For women, the corresponding rates were 43.2 (±14.0) and 68.4 (±12.3) per 100 000 per year, respectively. On average, rates for women increased by about 1.9% per year (P = 0.064), whereas rates for men declined by 1.7% per year (P = 0.019). The overall man to woman ratio decreased from 3.1 to 1.3 during the 30 years (P = 0.006). Incident stone rates were highest for men aged 60-69 years, whereas for women, they plateaued after age 30. Therefore, since 1970 overall NL incidence rates in Rochester have remained relatively flat. However, NL rates for men have declined, whereas rates for women appear to be increasing. The reasons remain to be determined.",
keywords = "Calcium oxalate, Incidence, Kidney stone, Nephrolithiasis, Sex",
author = "Lieske, {J. C.} and {Pe{\~n}a De La Vega}, {L. S.} and Slezak, {J. M.} and Bergstralh, {E. J.} and Leibson, {C. L.} and Ho, {K. L.} and Gettman, {M. T.}",
note = "Funding Information: We thank J. Zimmerman for excellent secretarial assistance. This work was supported by grants from the National Institutes of Health (DK 53399, DK 60707, and AR 30582), the Oxalosis and Hyperoxaluria Foundation, and the Mayo Foundation. Funding Information: Olmsted County, MN, USA (2000 census population, 124 277) and its central city Rochester (2000 census population, 85 806) are located in the southeastern part of the State, approximately 128 km from the nearest major metropolitan area. Population-based epidemiologic research in Olmsted County is facilitated by its relative geographic isolation. Nearly all of the medical care delivered to Olmsted County residents is provided by either the Mayo Clinic or the Olmsted Medical Center and their respective affiliated hospitals. 24 Since 1907, every Mayo Clinic patient has been assigned a unique identifier, and all information from every contact is contained within a single dossier (including office, emergency department, and nursing home visits and hospital in-patient or outpatient admissions). This detailed information includes a medical history, clinical assessments, consultation reports, dismissal summaries, laboratory and radiology results, and correspondence. The diagnoses assigned at each visit are coded and entered into continuously updated computer files. These files constitute the Rochester Epidemiology Project diagnostic index. With funding from the National Institutes of Health (Grant AR 30582), the diagnostic index and record linkage was expanded to include the other providers of medical care to local residents, including the Olmsted Medical Center and the few private practitioners in the area. Thus, the details of almost all of the medical care provided to the residents of Rochester are available for study. 24 ",
year = "2006",
month = feb,
doi = "10.1038/sj.ki.5000150",
language = "English (US)",
volume = "69",
pages = "760--764",
journal = "Kidney international",
issn = "0085-2538",
publisher = "Nature Publishing Group",
number = "4",
}