Renal response to repeated exposure to endotoxin: Implications for acute kidney injury

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12 Scopus citations


Zager and colleagues demonstrate that endotoxin tolerance is accompanied by an augmented inflammatory response in the kidney, the latter also exhibiting cholesterol-dependent cytoresistance. These novel findings are discussed mainly from the perspective of acute kidney injury and its prevention by preconditioning and the elicitation of cytoprotective pathways.

Original languageEnglish (US)
Pages (from-to)477-479
Number of pages3
JournalKidney international
Issue number6
StatePublished - Mar 13 2007


ASJC Scopus subject areas

  • Nephrology

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