Abstract
Amyloidosis results from the pathologic deposition of beta pleated sheet fibrils within various organs including the kidney. Most often, the deposition is composed of the well-known monoclonal immunoglobulin light chains (AL) or serum amyloid A protein (AA). Recently, a new type of amyloidogenic protein was discovered, leukocyte chemotactic factor 2 (LECT2). This type of amyloid tends to have an affinity to kidney and liver and is recognized as a distinct clinico-pathologic type of amyloidosis, presenting with varying degrees of impaired kidney function and proteinuria. Herein, a case of this uncommon novel amyloidosis is presented with a brief review of the literature.
Original language | English (US) |
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Pages (from-to) | 236-240 |
Number of pages | 5 |
Journal | Clinical nephrology |
Volume | 84 |
Issue number | 4 |
DOIs | |
State | Published - 2015 |
Keywords
- ALECT2
- Amyloidosis
- LECT2
- Leucozyte chemotactic factor 2
- Renal amyloidosis
ASJC Scopus subject areas
- Nephrology