Renal ablation using bilateral ureteral ligation for nephrotic syndrome due to renal amyloidosis

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1 Citation (Scopus)

Abstract

Nephrotic syndrome is common in immunoglobulin light chain amyloidosis (AL). In patients who do not achieve renal recovery, renal ablation has been reported for intractable proteinuria. We describe a patient with renal-limited AL who failed therapy and developed disabling proteinuria. He underwent laparoscopic ligation of the native ureters. Post-operatively, blood pressure improved. Hemodialysis was initiated. We conclude that bilateral ureteral ligation is a novel and minimally invasive method of renal ablation and may be considered for patients with refractory nephrotic syndrome.

Original languageEnglish (US)
Pages (from-to)153-154
Number of pages2
JournalClinical Kidney Journal
Volume5
Issue number2
DOIs
StatePublished - 2012

Fingerprint

Nephrotic Syndrome
Amyloidosis
Ligation
Kidney
Proteinuria
Immunoglobulin Light Chains
Ureter
Renal Dialysis
Blood Pressure
Therapeutics

Keywords

  • amyloidosis
  • nephrotic
  • ureteral ligation

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

Cite this

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abstract = "Nephrotic syndrome is common in immunoglobulin light chain amyloidosis (AL). In patients who do not achieve renal recovery, renal ablation has been reported for intractable proteinuria. We describe a patient with renal-limited AL who failed therapy and developed disabling proteinuria. He underwent laparoscopic ligation of the native ureters. Post-operatively, blood pressure improved. Hemodialysis was initiated. We conclude that bilateral ureteral ligation is a novel and minimally invasive method of renal ablation and may be considered for patients with refractory nephrotic syndrome.",
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AB - Nephrotic syndrome is common in immunoglobulin light chain amyloidosis (AL). In patients who do not achieve renal recovery, renal ablation has been reported for intractable proteinuria. We describe a patient with renal-limited AL who failed therapy and developed disabling proteinuria. He underwent laparoscopic ligation of the native ureters. Post-operatively, blood pressure improved. Hemodialysis was initiated. We conclude that bilateral ureteral ligation is a novel and minimally invasive method of renal ablation and may be considered for patients with refractory nephrotic syndrome.

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