Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease

Naima Covassin, Ariel B. Neikrug, Lianqi Liu, Jeanne Maglione, Loki Natarajan, Jody Corey-Bloom, Jose S. Loredo, Barton W. Palmer, Laura S. Redwine, Sonia Ancoli-Israel

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.

Original languageEnglish (US)
Pages (from-to)85-88
Number of pages4
JournalAutonomic Neuroscience: Basic and Clinical
Volume171
Issue number1-2
DOIs
StatePublished - 2012

Keywords

  • Heart rate variability
  • Parkinson's disease
  • Polysomnography
  • Sleep

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease'. Together they form a unique fingerprint.

Cite this