Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease

Naima Covassin; Ariel B. Neikrug; Lianqi Liu; Jeanne Maglione; Loki Natarajan; Jody Corey-Bloom; Jose S. Loredo; Barton W. Palmer; Laura S. Redwine; Sonia Ancoli-Israel

doi:10.1016/j.autneu.2012.10.003

Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease

Naima Covassin, Ariel B. Neikrug, Lianqi Liu, Jeanne Maglione, Loki Natarajan, Jody Corey-Bloom, Jose S. Loredo, Barton W. Palmer, Laura S. Redwine, Sonia Ancoli-Israel

Cardiovascular Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.

Original language	English (US)
Pages (from-to)	85-88
Number of pages	4
Journal	Autonomic Neuroscience: Basic and Clinical
Volume	171
Issue number	1-2
DOIs	https://doi.org/10.1016/j.autneu.2012.10.003
State	Published - 2012

Keywords

Heart rate variability
Parkinson's disease
Polysomnography
Sleep

ASJC Scopus subject areas

Endocrine and Autonomic Systems
Clinical Neurology
Cellular and Molecular Neuroscience

Access to Document

10.1016/j.autneu.2012.10.003

Cite this

Covassin, N., Neikrug, A. B., Liu, L., Maglione, J., Natarajan, L., Corey-Bloom, J., Loredo, J. S., Palmer, B. W., Redwine, L. S., & Ancoli-Israel, S. (2012). Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease. Autonomic Neuroscience: Basic and Clinical, 171(1-2), 85-88. https://doi.org/10.1016/j.autneu.2012.10.003

Covassin, N, Neikrug, AB, Liu, L, Maglione, J, Natarajan, L, Corey-Bloom, J, Loredo, JS, Palmer, BW, Redwine, LS & Ancoli-Israel, S 2012, 'Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease', Autonomic Neuroscience: Basic and Clinical, vol. 171, no. 1-2, pp. 85-88. https://doi.org/10.1016/j.autneu.2012.10.003

@article{ba180c4c4a35459c8579f5d9cd20a4e2,

title = "Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease",

abstract = "Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.",

keywords = "Heart rate variability, Parkinson's disease, Polysomnography, Sleep",

author = "Naima Covassin and Neikrug, {Ariel B.} and Lianqi Liu and Jeanne Maglione and Loki Natarajan and Jody Corey-Bloom and Loredo, {Jose S.} and Palmer, {Barton W.} and Redwine, {Laura S.} and Sonia Ancoli-Israel",

note = "Funding Information: The study was supported by NIA AG08415, UL1RR031980 (CTRI), the UCSD Stein Institute for Research on Aging and the Department of Veterans Affairs Center of Excellence for Stress and Mental Health (CESAMH). ",

year = "2012",

doi = "10.1016/j.autneu.2012.10.003",

language = "English (US)",

volume = "171",

pages = "85--88",

journal = "Autonomic Neuroscience: Basic and Clinical",

issn = "1566-0702",

publisher = "Elsevier",

number = "1-2",

}

TY - JOUR

T1 - Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease

AU - Covassin, Naima

AU - Neikrug, Ariel B.

AU - Liu, Lianqi

AU - Maglione, Jeanne

AU - Natarajan, Loki

AU - Corey-Bloom, Jody

AU - Loredo, Jose S.

AU - Palmer, Barton W.

AU - Redwine, Laura S.

AU - Ancoli-Israel, Sonia

N1 - Funding Information: The study was supported by NIA AG08415, UL1RR031980 (CTRI), the UCSD Stein Institute for Research on Aging and the Department of Veterans Affairs Center of Excellence for Stress and Mental Health (CESAMH).

PY - 2012

Y1 - 2012

N2 - Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.

AB - Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.

KW - Heart rate variability

KW - Parkinson's disease

KW - Polysomnography

KW - Sleep

UR - http://www.scopus.com/inward/record.url?scp=84869507006&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84869507006&partnerID=8YFLogxK

U2 - 10.1016/j.autneu.2012.10.003

DO - 10.1016/j.autneu.2012.10.003

M3 - Article

C2 - 23141523

AN - SCOPUS:84869507006

SN - 1566-0702

VL - 171

SP - 85

EP - 88

JO - Autonomic Neuroscience: Basic and Clinical

JF - Autonomic Neuroscience: Basic and Clinical

IS - 1-2

ER -

Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this