Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease

Naima Covassin, Ariel B. Neikrug, Lianqi Liu, Jeanne Maglione, Loki Natarajan, Jody Corey-Bloom, Jose S. Loredo, Barton W. Palmer, Laura S. Redwine, Sonia Ancoli-Israel

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.

Original languageEnglish (US)
Pages (from-to)85-88
Number of pages4
JournalAutonomic Neuroscience: Basic and Clinical
Volume171
Issue number1-2
DOIs
StatePublished - Nov 8 2012
Externally publishedYes

Fingerprint

Parkinson Disease
Sleep
Heart Rate
Polysomnography
Sleep Stages
REM Sleep

Keywords

  • Heart rate variability
  • Parkinson's disease
  • Polysomnography
  • Sleep

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Endocrine and Autonomic Systems

Cite this

Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease. / Covassin, Naima; Neikrug, Ariel B.; Liu, Lianqi; Maglione, Jeanne; Natarajan, Loki; Corey-Bloom, Jody; Loredo, Jose S.; Palmer, Barton W.; Redwine, Laura S.; Ancoli-Israel, Sonia.

In: Autonomic Neuroscience: Basic and Clinical, Vol. 171, No. 1-2, 08.11.2012, p. 85-88.

Research output: Contribution to journalArticle

Covassin, N, Neikrug, AB, Liu, L, Maglione, J, Natarajan, L, Corey-Bloom, J, Loredo, JS, Palmer, BW, Redwine, LS & Ancoli-Israel, S 2012, 'Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease', Autonomic Neuroscience: Basic and Clinical, vol. 171, no. 1-2, pp. 85-88. https://doi.org/10.1016/j.autneu.2012.10.003
Covassin, Naima ; Neikrug, Ariel B. ; Liu, Lianqi ; Maglione, Jeanne ; Natarajan, Loki ; Corey-Bloom, Jody ; Loredo, Jose S. ; Palmer, Barton W. ; Redwine, Laura S. ; Ancoli-Israel, Sonia. / Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease. In: Autonomic Neuroscience: Basic and Clinical. 2012 ; Vol. 171, No. 1-2. pp. 85-88.
@article{ba180c4c4a35459c8579f5d9cd20a4e2,
title = "Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease",
abstract = "Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.",
keywords = "Heart rate variability, Parkinson's disease, Polysomnography, Sleep",
author = "Naima Covassin and Neikrug, {Ariel B.} and Lianqi Liu and Jeanne Maglione and Loki Natarajan and Jody Corey-Bloom and Loredo, {Jose S.} and Palmer, {Barton W.} and Redwine, {Laura S.} and Sonia Ancoli-Israel",
year = "2012",
month = "11",
day = "8",
doi = "10.1016/j.autneu.2012.10.003",
language = "English (US)",
volume = "171",
pages = "85--88",
journal = "Autonomic Neuroscience: Basic and Clinical",
issn = "1566-0702",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Relationships between clinical characteristics and nocturnal cardiac autonomic activity in Parkinson's disease

AU - Covassin, Naima

AU - Neikrug, Ariel B.

AU - Liu, Lianqi

AU - Maglione, Jeanne

AU - Natarajan, Loki

AU - Corey-Bloom, Jody

AU - Loredo, Jose S.

AU - Palmer, Barton W.

AU - Redwine, Laura S.

AU - Ancoli-Israel, Sonia

PY - 2012/11/8

Y1 - 2012/11/8

N2 - Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.

AB - Background: The aim of the present study was to explore the association between Parkinson's disease (PD) clinical characteristics and cardiac autonomic control across sleep stages. Methods: Frequency-domain heart rate variability (HRV) measures were estimated in 18 PD patients undergoing a night of polysomnography. Results: Significant relationships were found between PD severity and nocturnal HRV indices. The associations were restricted to rapid eye movement (R) sleep. Conclusions: The progressive nocturnal cardiac autonomic impairment occurring with more severe PD can be subclinical emerging only during conditions requiring active modulation of physiological functions such as R-sleep.

KW - Heart rate variability

KW - Parkinson's disease

KW - Polysomnography

KW - Sleep

UR - http://www.scopus.com/inward/record.url?scp=84869507006&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84869507006&partnerID=8YFLogxK

U2 - 10.1016/j.autneu.2012.10.003

DO - 10.1016/j.autneu.2012.10.003

M3 - Article

C2 - 23141523

AN - SCOPUS:84869507006

VL - 171

SP - 85

EP - 88

JO - Autonomic Neuroscience: Basic and Clinical

JF - Autonomic Neuroscience: Basic and Clinical

SN - 1566-0702

IS - 1-2

ER -