Relationship between Dihydropyrimidine Dehydrogenase Activity and Plasma 5-Fluorouracil Levels with Evidence for Orcadian Variation of Enzyme Activity and Plasma Drug Levels in Cancer Patients Receiving 5-Fluorouracil by Protracted Continuous Infusion

Barry E. Harris, Ruiling Song, Robert B. Diasio, Seng Jaw Soong

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442 Scopus citations

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Medicine & Life Sciences