Abstract
Red ginseng has been used as an ergogenic aid for endurance exercise. In this study, the effect of aqueous extract of Red ginseng on the endurance in treadmill exercise and 5-hydroxytryptamine (serotonin) synthesis and tryptophan hydroxylase expression in the dorsal raphe of rats were studied. Rats receiving Red ginseng showed increased time to exhaustion for treadmill running, and Red ginseng treatment inhibited exercise-induced increases in 5-hydroxy-tryptamine synthesis and tryptophan hydroxylase expression in the dorsal raphe. These results suggest that the suppressive effect of Red ginseng on serotonin level during exercise is a possible ergogenic mechanism of Red ginseng.
Original language | English (US) |
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Pages (from-to) | 218-221 |
Number of pages | 4 |
Journal | Journal of Pharmacological Sciences |
Volume | 93 |
Issue number | 2 |
DOIs | |
State | Published - Oct 2003 |
Keywords
- Red ginseng
- Serotonin
- Treadmill exercise
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology