Radioguidance for nonpalpable primary lesions and sentinel lymph node(s)

Richard J. Gray, Rosemary Giuliano, Emilia L. Dauway, Charles E. Cox, Douglas S. Reintgen

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Background: Radioguided surgery can also be used for the simultaneous guidance to a nonpalpable primary tumor and sentinel lymph nodes. Methods: Retrospective review of a prospective database. The surgeon used a gamma probe for guidance to an iodine-125 labeled titanium seed at the primary lesion and technetium-99 labeled sulfur colloid at the sentinel lymph node. Results: Forty-three patients with nonpalpable breast carcinoma underwent dual isotope radioguided surgery. The radioactive seed and primary lesion were retrieved in the first excision in all 44 patients (100%). Eleven patients (25%) had pathologically involved margins. Sentinel lymph node mapping was successful in 42 patients (98%). A mean of 2.4 sentinel nodes were excised and metastatic carcinoma was present in four patients (10%). Conclusions: Dual isotopes can be effectively used in breast cancer patients for simultaneous radioguidance to both a nonpalpable primary lesion and sentinel lymph node and allows for improved logistics.

Original languageEnglish (US)
Pages (from-to)404-406
Number of pages3
JournalAmerican Journal of Surgery
Volume182
Issue number4
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Isotopes
Seeds
Breast Neoplasms
Technetium
Colloids
Titanium
Sulfur
Iodine
Sentinel Lymph Node
Databases
Carcinoma
Neoplasms
Surgeons
cyhalothrin

Keywords

  • Radioguided surgery
  • Sentinel lymph node
  • Wire localization

ASJC Scopus subject areas

  • Surgery

Cite this

Gray, R. J., Giuliano, R., Dauway, E. L., Cox, C. E., & Reintgen, D. S. (2001). Radioguidance for nonpalpable primary lesions and sentinel lymph node(s). American Journal of Surgery, 182(4), 404-406. https://doi.org/10.1016/S0002-9610(01)00716-4

Radioguidance for nonpalpable primary lesions and sentinel lymph node(s). / Gray, Richard J.; Giuliano, Rosemary; Dauway, Emilia L.; Cox, Charles E.; Reintgen, Douglas S.

In: American Journal of Surgery, Vol. 182, No. 4, 2001, p. 404-406.

Research output: Contribution to journalArticle

Gray, RJ, Giuliano, R, Dauway, EL, Cox, CE & Reintgen, DS 2001, 'Radioguidance for nonpalpable primary lesions and sentinel lymph node(s)', American Journal of Surgery, vol. 182, no. 4, pp. 404-406. https://doi.org/10.1016/S0002-9610(01)00716-4
Gray, Richard J. ; Giuliano, Rosemary ; Dauway, Emilia L. ; Cox, Charles E. ; Reintgen, Douglas S. / Radioguidance for nonpalpable primary lesions and sentinel lymph node(s). In: American Journal of Surgery. 2001 ; Vol. 182, No. 4. pp. 404-406.
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