Quantitative assessment of cardiac motion using multiphase computed tomography imaging with application to cardiac ablation therapy

A. C. Hasnain, A. Suzuki, S. Wang, H. Konishi, S. Hohmann, L. K. Newman, K. D. Parker, A. J. Deisher, D. L. Packer, M. E. Rettmann

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Cardiac arrhythmias, a condition in which the heart beats irregularly, are typically treated with drug or cardiac ablation therapy. More recently, external beam ablation therapy has been proposed as a potential approach for treating cardiac arrhythmias. Currently, a significant challenge regarding external beam ablation therapy in the heart is compensation for cardiac motion to ensure precise targeting. Porcine animal models are often used for evaluating image-guided intervention systems for cardiac applications; however, to date there have been relatively few studies evaluating motion in the swine heart. In this study, we model and quantify cardiac motion in the left atrium and left ventricle of three beating porcine hearts by tracking anatomic landmarks across twenty phases of the cardiac cycle from multi-phase computed tomography images. 10 landmarks are tracked for each porcine heart, 5 in the left atrium and 5 in the left ventricle. The mean (std) displacement for the 5 left atrial landmarks is 5.5(3.5) mm in x, 5.0(2.9) mm in y, and 5.6(3.3) mm in z. The mean (std) displacement for the 5 left ventricular landmarks is 7.1(3.8) mm in x, 9.9(5.2) mm in y, and 7.7(3.1) mm in z.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2018
Subtitle of host publicationImage-Guided Procedures, Robotic Interventions, and Modeling
EditorsBaowei Fei, Robert J. Webster
PublisherSPIE
ISBN (Electronic)9781510616417
DOIs
StatePublished - Jan 1 2018
EventMedical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling - Houston, United States
Duration: Feb 12 2018Feb 15 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10576
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling
CountryUnited States
CityHouston
Period2/12/182/15/18

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Hasnain, A. C., Suzuki, A., Wang, S., Konishi, H., Hohmann, S., Newman, L. K., Parker, K. D., Deisher, A. J., Packer, D. L., & Rettmann, M. E. (2018). Quantitative assessment of cardiac motion using multiphase computed tomography imaging with application to cardiac ablation therapy. In B. Fei, & R. J. Webster (Eds.), Medical Imaging 2018: Image-Guided Procedures, Robotic Interventions, and Modeling [105762F] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10576). SPIE. https://doi.org/10.1117/12.2295438