Quantitation of regional myocardial function during short-lived events with ultrasound imaging

E. M. McMahon, J. Wang, J. Korinek, S. Urheim, M. Belohlavek

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Short-lived (tens through hundreds of milliseconds) cardiac motion events, such as post-systolic thickening, have diagnostic importance and are detectable by echocardiography. Selection and quantitative analysis of these events cannot be adequately done using conventional clinical measurements of heart function. We have developed an interactive tool using MATLAB (The MathWorks, Inc., Natick, MA) that allows the user to select events in time from graphs of available data including ECG, strain, left ventricular (LV) pressure, and the time derivative of the LV pressure trace. After selection of an event in time, the program calculates the area for that section of a pressure-strain loop, which is known to correlate to myocardial contraction work. Using the new tool, we present data from a canine model of prolonged (1-2 week) local myocardial ischemia. We found that following ischemia, a proportion of the loop area in the affected cardiac muscle takes place during a postejection phase. That is, the muscle contracts but during the postejection (post-systolic) phase and hence no longer contributes to ejecting blood to circulation.

Original languageEnglish (US)
Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationMacro to Nano
Pages508-511
Number of pages4
StatePublished - Dec 1 2004
Event2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano - Arlington, VA, United States
Duration: Apr 15 2004Apr 18 2004

Publication series

Name2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume1

Other

Other2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
CountryUnited States
CityArlington, VA
Period4/15/044/18/04

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    McMahon, E. M., Wang, J., Korinek, J., Urheim, S., & Belohlavek, M. (2004). Quantitation of regional myocardial function during short-lived events with ultrasound imaging. In 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (pp. 508-511). (2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano; Vol. 1).