Quantitation of hematoporphyrin derivative in human gliomas, experimental central nervous system tumors, and normal tissues

R. E. Wharen, R. E. Anderson, E. R. Laws

Research output: Contribution to journalArticle

66 Scopus citations

Abstract

A simple and reproducible method of quantitating the amount of hematoporphyrin derivative by fluorescence microscopy in biopsies of tumors from patients undergoing photoradiation therapy is presented, substantiated by laboratory studies of experimental central nervous system tumors and normal rat tissues. The literature regarding the quantitation of hematoporphyrin is reviewed, and implications of this study for the future application of photoradiation therapy and the design of laboratory studies are discussed.

Original languageEnglish (US)
Pages (from-to)446-450
Number of pages5
JournalNeurosurgery
Volume12
Issue number4
DOIs
StatePublished - Jan 1 1983

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ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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