Quantitation of hematoporphyrin derivative in human gliomas, experimental central nervous system tumors, and normal tissues

R. E. Wharen; R. E. Anderson; E. R. Laws

doi:10.1227/00006123-198304000-00013

Quantitation of hematoporphyrin derivative in human gliomas, experimental central nervous system tumors, and normal tissues

R. E. Wharen, R. E. Anderson, E. R. Laws

Neurosurgery

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

A simple and reproducible method of quantitating the amount of hematoporphyrin derivative by fluorescence microscopy in biopsies of tumors from patients undergoing photoradiation therapy is presented, substantiated by laboratory studies of experimental central nervous system tumors and normal rat tissues. The literature regarding the quantitation of hematoporphyrin is reviewed, and implications of this study for the future application of photoradiation therapy and the design of laboratory studies are discussed.

Original language	English (US)
Pages (from-to)	446-450
Number of pages	5
Journal	Neurosurgery
Volume	12
Issue number	4
DOIs	https://doi.org/10.1227/00006123-198304000-00013
State	Published - 1983

ASJC Scopus subject areas

Surgery
Clinical Neurology

Access to Document

10.1227/00006123-198304000-00013

Cite this

@article{9a2af895dfac43a18686920ae5ae90e1,

title = "Quantitation of hematoporphyrin derivative in human gliomas, experimental central nervous system tumors, and normal tissues",

abstract = "A simple and reproducible method of quantitating the amount of hematoporphyrin derivative by fluorescence microscopy in biopsies of tumors from patients undergoing photoradiation therapy is presented, substantiated by laboratory studies of experimental central nervous system tumors and normal rat tissues. The literature regarding the quantitation of hematoporphyrin is reviewed, and implications of this study for the future application of photoradiation therapy and the design of laboratory studies are discussed.",

author = "Wharen, {R. E.} and Anderson, {R. E.} and Laws, {E. R.}",

year = "1983",

doi = "10.1227/00006123-198304000-00013",

language = "English (US)",

volume = "12",

pages = "446--450",

journal = "Neurosurgery",

issn = "0148-396X",

publisher = "Lippincott Williams and Wilkins",

number = "4",

}

TY - JOUR

T1 - Quantitation of hematoporphyrin derivative in human gliomas, experimental central nervous system tumors, and normal tissues

AU - Wharen, R. E.

AU - Anderson, R. E.

AU - Laws, E. R.

PY - 1983

Y1 - 1983

N2 - A simple and reproducible method of quantitating the amount of hematoporphyrin derivative by fluorescence microscopy in biopsies of tumors from patients undergoing photoradiation therapy is presented, substantiated by laboratory studies of experimental central nervous system tumors and normal rat tissues. The literature regarding the quantitation of hematoporphyrin is reviewed, and implications of this study for the future application of photoradiation therapy and the design of laboratory studies are discussed.

AB - A simple and reproducible method of quantitating the amount of hematoporphyrin derivative by fluorescence microscopy in biopsies of tumors from patients undergoing photoradiation therapy is presented, substantiated by laboratory studies of experimental central nervous system tumors and normal rat tissues. The literature regarding the quantitation of hematoporphyrin is reviewed, and implications of this study for the future application of photoradiation therapy and the design of laboratory studies are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0020569120&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020569120&partnerID=8YFLogxK

U2 - 10.1227/00006123-198304000-00013

DO - 10.1227/00006123-198304000-00013

M3 - Article

C2 - 6222266

AN - SCOPUS:0020569120

SN - 0148-396X

VL - 12

SP - 446

EP - 450

JO - Neurosurgery

JF - Neurosurgery

IS - 4

ER -

Quantitation of hematoporphyrin derivative in human gliomas, experimental central nervous system tumors, and normal tissues

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this