Putting tumours in context

Mina J. Bissell, Derek C Radisky

Research output: Contribution to journalArticle

1552 Scopus citations

Abstract

The interactions between cancer cells and their micro- and macroenvironment create a context that promotes tumour growth and protects it from immune attack. The functional association of cancer cells with their surrounding tissues forms a new 'organ' that changes as malignancy progresses. Investigation of this process might provide new insights into the mechanisms of tumorigenesis and could also lead to new therapeutic targets.

Original languageEnglish (US)
Pages (from-to)46-54
Number of pages9
JournalNature Reviews Cancer
Volume1
Issue number1
StatePublished - 2001
Externally publishedYes

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ASJC Scopus subject areas

  • Cancer Research

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