Pulmonary pyoderma gangrenosum without cutaneous manifestations

Kenneth Kazuto Sakata, Sudheer Penupolu, Thomas Vail Colby, Michael Gotway, Lewis Jon Wesselius

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Pyoderma gangrenosum is a chronic sterile skin disorder that is frequently seen in association with systemic disorders such as inflammatory bowel disease. Extracutaneous pyoderma gangrenosum is rare and most commonly occurs in the lungs. It is particularly unusual for extracutaneous pyoderma gangrenosum to manifest prior to skin findings and without an associated systemic disorder. A 19-year-old white man presented with shortness of breath and a productive cough. His skin exam was normal. Unenhanced chest computed tomography showed peripheral consolidations, areas of cavitation, nodules and bilateral pleural effusions. A bronchoalveolar lavage and an autoimmune panel were unremarkable. Right lung wedge biopsies via thoracostomy was performed and showed pulmonary pyoderma gangrenosum. He was treated with corticosteroids and has returned back to his baseline. This is the first case of pulmonary pyoderma gangrenosum without any associated underlying systemic disorder and without any cutaneous manifestations to date. Serial follow-ups are necessary to assess for the development of an associated systemic disorder or skin lesions.

Original languageEnglish (US)
Pages (from-to)508-511
Number of pages4
JournalClinical Respiratory Journal
Volume10
Issue number4
DOIs
StatePublished - Jul 1 2016

Keywords

  • extracutaneous pyoderma gangrenosum
  • granulomatosis with polyangiitis
  • inflammatory bowel disease
  • pulmonary pyoderma gangrenosum

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Immunology and Allergy
  • Genetics(clinical)

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