Pulmonary mantle cell lymphoma: A rare manifestation of an uncommon condition

Zachary S. Depew, Robert Vassallo

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Herein we describe the case of a 64-year old man with a history of mantle cell lymphoma found to have evidence of pulmonary parenchymal involvement by recurrence of his lymphoma. While lung involvement is not necessarily uncommon with Non-Hodgkin's lymphomas as a group, it is very rare for mantle cell lymphoma to involve the lung parenchyma. In addition, the radiographic manifestation of his pulmonary lymphoma as a discrete FDGavid ground-glass lesion on chest imaging was also distinctly uncommon for pulmonary lymphoma which classically appears in one of three patterns: scattered ill-defined nodules, a bronchovascular/lymphangitic process, or pneumonic/alveolar consolidation effectively indistinguishable from bacterial pneumonia. Due to significant underlying lung disease our patient was not a candidate for high-dose conditioning and autologous stem cell transplantation. He was ultimately treated with rituximab and cladribine therapy and had early signs of clinical response at last correspondence.

Original languageEnglish (US)
Pages (from-to)30-31
Number of pages2
JournalRare Tumors
Volume4
Issue number1
DOIs
StatePublished - Apr 17 2012

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Keywords

  • Mantle cell lymphoma
  • Non-Hodgkin's lymphoma
  • Pulmonary lymphoma

ASJC Scopus subject areas

  • Histology
  • Oncology

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