TY - JOUR
T1 - Pulmonary contraindications, indications and MELD exceptions for liver transplantation
T2 - A contemporary view and look forward
AU - Krowka, Michael J.
AU - Wiesner, Russell H.
AU - Heimbach, Julie K.
PY - 2013/8
Y1 - 2013/8
N2 - Summary Pulmonary concerns in liver transplant candidates have intraoperative and outcome implications. Evolving MELD exception policies address transplant priority for problems such as hepatopulmonary syndrome, portopulmonary hypertension, and hemorrhagic hereditary telangiectasia. Other pulmonary issues such as refractory hepatic hydrothorax, advanced chronic obstructive lung disease (including alpha-1 antitrypsin deficiency) and indeterminate pulmonary nodules may affect liver transplant consideration. Herein, we discuss current pulmonary-related contraindications, indications and MELD exception policies for liver transplantation, suggesting future considerations.
AB - Summary Pulmonary concerns in liver transplant candidates have intraoperative and outcome implications. Evolving MELD exception policies address transplant priority for problems such as hepatopulmonary syndrome, portopulmonary hypertension, and hemorrhagic hereditary telangiectasia. Other pulmonary issues such as refractory hepatic hydrothorax, advanced chronic obstructive lung disease (including alpha-1 antitrypsin deficiency) and indeterminate pulmonary nodules may affect liver transplant consideration. Herein, we discuss current pulmonary-related contraindications, indications and MELD exception policies for liver transplantation, suggesting future considerations.
KW - Alpha-1 antitrypsin deficiency
KW - Hepatic hydrothorax
KW - Hepatopulmonary syndrome
KW - Hereditary hemorrhagic telangiectasia
KW - Portopulmonary hypertension
KW - Pulmonary nodules
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U2 - 10.1016/j.jhep.2013.03.026
DO - 10.1016/j.jhep.2013.03.026
M3 - Review article
C2 - 23557870
AN - SCOPUS:84880301837
SN - 0168-8278
VL - 59
SP - 367
EP - 374
JO - Journal of hepatology
JF - Journal of hepatology
IS - 2
ER -