Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism

Logan P. Haug; Matthew A. Zarka; Jonathan D'Cunha; Francis X. Downey; Mahesh Seetharam; Ming Yang

doi:10.1097/RLU.0000000000004306

Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism

Logan P. Haug, Matthew A. Zarka, Jonathan D'Cunha, Francis X. Downey, Mahesh Seetharam, Ming Yang

Diagnostic Radiology

Research output: Contribution to journal › Review article › peer-review

Abstract

A 39-year-old man presented with progressive dyspnea and lower extremity edema. Doppler ultrasound demonstrated bilateral leg partially occluded venous thromboses. A V/Q scan revealed a mismatched perfusion defect involving the entire right middle and lower lobes. Subsequent CT pulmonary angiogram revealed a mass lesion occluding the right interlobar pulmonary artery. Endobronchial ultrasound-guided fine-needle aspiration of the mass was concerning for neoplasm. 18F-FDG PET/CT demonstrated marked hypermetabolism of the mass lesion. Patient underwent transmediastinal right pneumonectomy with histopathologic diagnosis of pulmonary artery angiomatoid fibrous histiocytoma, a rare etiology mimicking large pulmonary artery embolism.

Original language	English (US)
Pages (from-to)	E738-E739
Journal	Clinical nuclear medicine
Volume	47
Issue number	12
DOIs	https://doi.org/10.1097/RLU.0000000000004306
State	Published - Dec 1 2022

Keywords

F-FDG PET/CT
angiomatoid fibrous histiocytoma
pulmonary artery
V/Q scan

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/RLU.0000000000004306

Cite this

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title = "Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism",

abstract = "A 39-year-old man presented with progressive dyspnea and lower extremity edema. Doppler ultrasound demonstrated bilateral leg partially occluded venous thromboses. A V/Q scan revealed a mismatched perfusion defect involving the entire right middle and lower lobes. Subsequent CT pulmonary angiogram revealed a mass lesion occluding the right interlobar pulmonary artery. Endobronchial ultrasound-guided fine-needle aspiration of the mass was concerning for neoplasm. 18F-FDG PET/CT demonstrated marked hypermetabolism of the mass lesion. Patient underwent transmediastinal right pneumonectomy with histopathologic diagnosis of pulmonary artery angiomatoid fibrous histiocytoma, a rare etiology mimicking large pulmonary artery embolism.",

keywords = "F-FDG PET/CT, angiomatoid fibrous histiocytoma, pulmonary artery, V/Q scan",

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year = "2022",

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doi = "10.1097/RLU.0000000000004306",

language = "English (US)",

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T1 - Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism

AU - Haug, Logan P.

AU - Zarka, Matthew A.

AU - D'Cunha, Jonathan

AU - Downey, Francis X.

AU - Seetharam, Mahesh

AU - Yang, Ming

PY - 2022/12/1

Y1 - 2022/12/1

N2 - A 39-year-old man presented with progressive dyspnea and lower extremity edema. Doppler ultrasound demonstrated bilateral leg partially occluded venous thromboses. A V/Q scan revealed a mismatched perfusion defect involving the entire right middle and lower lobes. Subsequent CT pulmonary angiogram revealed a mass lesion occluding the right interlobar pulmonary artery. Endobronchial ultrasound-guided fine-needle aspiration of the mass was concerning for neoplasm. 18F-FDG PET/CT demonstrated marked hypermetabolism of the mass lesion. Patient underwent transmediastinal right pneumonectomy with histopathologic diagnosis of pulmonary artery angiomatoid fibrous histiocytoma, a rare etiology mimicking large pulmonary artery embolism.

AB - A 39-year-old man presented with progressive dyspnea and lower extremity edema. Doppler ultrasound demonstrated bilateral leg partially occluded venous thromboses. A V/Q scan revealed a mismatched perfusion defect involving the entire right middle and lower lobes. Subsequent CT pulmonary angiogram revealed a mass lesion occluding the right interlobar pulmonary artery. Endobronchial ultrasound-guided fine-needle aspiration of the mass was concerning for neoplasm. 18F-FDG PET/CT demonstrated marked hypermetabolism of the mass lesion. Patient underwent transmediastinal right pneumonectomy with histopathologic diagnosis of pulmonary artery angiomatoid fibrous histiocytoma, a rare etiology mimicking large pulmonary artery embolism.

KW - F-FDG PET/CT

KW - angiomatoid fibrous histiocytoma

KW - pulmonary artery

KW - V/Q scan

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ER -

Pulmonary Artery Angiomatoid Fibrous Histiocytoma Mimicking a Large Pulmonary Embolism

Abstract

Keywords

ASJC Scopus subject areas

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