TY - JOUR
T1 - Prosthetic joint infection
AU - Anguita-Alonso, Paloma
AU - Hanssen, Arlen D.
AU - Patel, Robin
N1 - Funding Information:
Paloma Anguita-Alonso is supported by a Grant of ‘Instituto de Salud Carlos III’ of the Spanish Ministry of Health.
PY - 2005/10
Y1 - 2005/10
N2 - Infection is the second most common cause of prosthetic joint failure. Signs and symptoms associated with prosthetic joint infection may develop weeks or even years following arthroplasty. While some patients with prosthetic joint infection present with findings consistent with acute septic arthritis, many present with pain alone. Morbidity and cost associated with repeat surgery, prolonged medical treatment and joint immobilization render importance to the accurate and timely diagnosis, and appropriate treatment of prosthetic joint infection. No consensus exists, however, in terms of the most cost-effective diagnostic methods or the ideal medical and/or surgical interventions. This review describes diagnostic tests and available treatment for prosthetic joint infection and gives a practical approach to this challenging clinical entity.
AB - Infection is the second most common cause of prosthetic joint failure. Signs and symptoms associated with prosthetic joint infection may develop weeks or even years following arthroplasty. While some patients with prosthetic joint infection present with findings consistent with acute septic arthritis, many present with pain alone. Morbidity and cost associated with repeat surgery, prolonged medical treatment and joint immobilization render importance to the accurate and timely diagnosis, and appropriate treatment of prosthetic joint infection. No consensus exists, however, in terms of the most cost-effective diagnostic methods or the ideal medical and/or surgical interventions. This review describes diagnostic tests and available treatment for prosthetic joint infection and gives a practical approach to this challenging clinical entity.
KW - Biofilm
KW - Local antimicrobial delivery
KW - Prosthetic joint infection
KW - Staphylococci
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U2 - 10.1586/14787210.3.5.797
DO - 10.1586/14787210.3.5.797
M3 - Review article
C2 - 16207171
AN - SCOPUS:27544470885
SN - 1478-7210
VL - 3
SP - 797
EP - 804
JO - Expert Review of Anti-Infective Therapy
JF - Expert Review of Anti-Infective Therapy
IS - 5
ER -