Prostate cancer metastasizing to the small bowel

Navreet Malhi-Chowla, Herbert C. Wolfsen, David Menke, Timothy A. Woodward

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Although prostate cancer is one of the most commonly encountered malignancies in clinical practice, it is very unusual for prostate cancer to metastasize to the small bowel. Our search of the literature found no such cases published from 1966 to the present. We report the case of a 69-year-old man who presented for evaluation of anasarca and anorexia. He had a history of prostate cancer diagnosed 9 years before and had undergone a radical prostatectomy with subsequent radiotherapy for positive tumor margins. He developed anasarca 2 years before presentation to us. His serum albumin ranged between 1.5 and 2.5 g/dL. Upper endoscopy was performed for possible protein-losing enteropathy and the appearance of gastric and duodenal mucosa was found to be normal. Random small bowel biopsies revealed submucosal infiltrating adenocarcinoma with positive prostate-specific antigen stains consistent with the diagnosis of prostate cancer metastatic to the small bowel. This is a rare presentation of metastatic prostate cancer. Even though prostate cancer is the most commonly diagnosed cancer in American men, antemortem diagnosis of small bowel metastasis has not been reported. In patients with unexplained anasarca, especially with a history of malignancy, an upper endoscopy with small bowel biopsy may be useful in establishing the diagnosis.

Original languageEnglish (US)
Pages (from-to)439-440
Number of pages2
JournalJournal of Clinical Gastroenterology
Volume32
Issue number5
DOIs
StatePublished - 2001

Fingerprint

Prostatic Neoplasms
Edema
Endoscopy
Neoplasms
Protein-Losing Enteropathies
Biopsy
Anorexia
Prostate-Specific Antigen
Prostatectomy
Gastric Mucosa
Serum Albumin
Adenocarcinoma
Coloring Agents
Radiotherapy
Neoplasm Metastasis

Keywords

  • Adenocarcinoma
  • Anasarca
  • Prostate cancer
  • Small bowel metastasis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Malhi-Chowla, N., Wolfsen, H. C., Menke, D., & Woodward, T. A. (2001). Prostate cancer metastasizing to the small bowel. Journal of Clinical Gastroenterology, 32(5), 439-440. https://doi.org/10.1097/00004836-200105000-00017

Prostate cancer metastasizing to the small bowel. / Malhi-Chowla, Navreet; Wolfsen, Herbert C.; Menke, David; Woodward, Timothy A.

In: Journal of Clinical Gastroenterology, Vol. 32, No. 5, 2001, p. 439-440.

Research output: Contribution to journalArticle

Malhi-Chowla, N, Wolfsen, HC, Menke, D & Woodward, TA 2001, 'Prostate cancer metastasizing to the small bowel', Journal of Clinical Gastroenterology, vol. 32, no. 5, pp. 439-440. https://doi.org/10.1097/00004836-200105000-00017
Malhi-Chowla, Navreet ; Wolfsen, Herbert C. ; Menke, David ; Woodward, Timothy A. / Prostate cancer metastasizing to the small bowel. In: Journal of Clinical Gastroenterology. 2001 ; Vol. 32, No. 5. pp. 439-440.
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