Prostate cancer-Associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4

Xiangpeng Dai, Wenjian Gan, Xiaoning Li, Shangqian Wang, Wei Zhang, Ling Huang, Shengwu Liu, Qing Zhong, Jianping Guo, Jinfang Zhang, Ting Chen, Kouhei Shimizu, Francisco Beca, Mirjam Blattner, Divya Vasudevan, Dennis L. Buckley, Jun Qi, Lorenz Buser, Pengda Liu, Hiroyuki InuzukaAndrew H. Beck, Liewei Wang, Peter J. Wild, Levi A. Garraway, Mark A. Rubin, Christopher E. Barbieri, Kwok Kin Wong, Senthil K. Muthuswamy, Jiaoti Huang, Yu Chen, James E. Bradner, Wenyi Wei

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Medicine & Life Sciences

Chemical Compounds