TY - JOUR
T1 - Prospective surveillance and risk reduction of cancer treatment-related lymphedema
T2 - Systematic review and meta-analysis
AU - Ding, Jingyi Francess
AU - Hasan, Bashar
AU - Malandris, Konstantinos
AU - Farah, Magdoleen H.
AU - Manolopoulos, Apostolos
AU - Ginex, Pamela K.
AU - Anbari, Allison B.
AU - Nayfeh, Tarek
AU - Rajjoub, Moutie Rami
AU - Benkhadra, Raed
AU - Prokop, Larry J.
AU - Morgan, Rebecca L.
AU - Hassan Murad, M.
N1 - Publisher Copyright:
© 2020 Oncology Nursing Society. All rights reserved.
PY - 2020
Y1 - 2020
N2 - PROBLEM IDENTIFICATION: Secondary lymphedema is a chronic condition that may result from cancer-related treatments. Evidence is emerging on prospective surveillance and risk reduction. LITERATURE SEARCH: Databases were systematically searched through April 1, 2019, for comparative studies evaluating interventions aiming to prevent lymphedema in patients with cancer. DATA EVALUATION: A random-effects model was used to perform meta-analysis, when appropriate. SYNTHESIS: A total of 26 studies (4,095 patients) were included, with 23 providing data sufficient for meta-analysis. Surveillance programs increased the likelihood of detecting lymphedema. Physiotherapy, exercise programs, and delayed exercise reduced the incidence of lymphedema. IMPLICATIONS FOR RESEARCH: Future research should standardize (a) evidence-based interventions to reduce the development of lymphedema and increase the likelihood of early detection and (b) outcome measures to build a body of evidence that leads to practice change.
AB - PROBLEM IDENTIFICATION: Secondary lymphedema is a chronic condition that may result from cancer-related treatments. Evidence is emerging on prospective surveillance and risk reduction. LITERATURE SEARCH: Databases were systematically searched through April 1, 2019, for comparative studies evaluating interventions aiming to prevent lymphedema in patients with cancer. DATA EVALUATION: A random-effects model was used to perform meta-analysis, when appropriate. SYNTHESIS: A total of 26 studies (4,095 patients) were included, with 23 providing data sufficient for meta-analysis. Surveillance programs increased the likelihood of detecting lymphedema. Physiotherapy, exercise programs, and delayed exercise reduced the incidence of lymphedema. IMPLICATIONS FOR RESEARCH: Future research should standardize (a) evidence-based interventions to reduce the development of lymphedema and increase the likelihood of early detection and (b) outcome measures to build a body of evidence that leads to practice change.
KW - Cancer treatment
KW - Lymphedema
KW - Meta-analysis
KW - Systematic review
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UR - http://www.scopus.com/inward/citedby.url?scp=85089794297&partnerID=8YFLogxK
U2 - 10.1188/20.ONF.E161-E170
DO - 10.1188/20.ONF.E161-E170
M3 - Review article
C2 - 32830796
AN - SCOPUS:85089794297
SN - 0190-535X
VL - 47
SP - E161-E170
JO - Oncology nursing forum
JF - Oncology nursing forum
IS - 5
ER -