Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery

Judy C Boughey, Farzin Goravanchi, Ronald N. Parris, Spencer S. Kee, Alicia M. Kowalski, John C. Frenzel, Isabelle Bedrosian, Funda Meric-Bernstam, Kelly K. Hunt, Frederick C. Ames, Henry M. Kuerer, Anthony Lucci

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Background: The goal of the current study was to evaluate the effect of regional anesthesia using paravertebral block (PVB) on postoperative pain after breast surgery. Methods: Patients undergoing unilateral breast surgery without reconstruction were randomized to general anesthesia (GA) only or PVB with GA and pain scores assessed. Results: Eighty patients were randomized (41 to GA and 39 to PVB with GA). Operative times were not significantly different between groups. Pain scores were lower after PVB compared to GA at 1 hour (1 vs 3, P = .006) and 3 hours (0 vs 2, P = .001) but not at later time points. The overall worst pain experienced was lower with PVB (3 vs 5, P = .02). More patients were pain-free in the PVB group at 1 hour (44% vs 17%, P = .014) and 3 hours (54% vs 17%, P = .005) postoperatively. Conclusions: PVB significantly decreases postoperative pain up to 3 hours after breast cancer surgery.

Original languageEnglish (US)
Pages (from-to)720-725
Number of pages6
JournalAmerican Journal of Surgery
Volume198
Issue number5
DOIs
StatePublished - Nov 2009
Externally publishedYes

Fingerprint

General Anesthesia
Breast Neoplasms
Postoperative Pain
Pain
Breast
Conduction Anesthesia
Operative Time

Keywords

  • Breast surgery
  • Length of stay
  • Pain control
  • Paravertebral block
  • Postoperative pain
  • Regional anesthesia

ASJC Scopus subject areas

  • Surgery

Cite this

Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery. / Boughey, Judy C; Goravanchi, Farzin; Parris, Ronald N.; Kee, Spencer S.; Kowalski, Alicia M.; Frenzel, John C.; Bedrosian, Isabelle; Meric-Bernstam, Funda; Hunt, Kelly K.; Ames, Frederick C.; Kuerer, Henry M.; Lucci, Anthony.

In: American Journal of Surgery, Vol. 198, No. 5, 11.2009, p. 720-725.

Research output: Contribution to journalArticle

Boughey, JC, Goravanchi, F, Parris, RN, Kee, SS, Kowalski, AM, Frenzel, JC, Bedrosian, I, Meric-Bernstam, F, Hunt, KK, Ames, FC, Kuerer, HM & Lucci, A 2009, 'Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery', American Journal of Surgery, vol. 198, no. 5, pp. 720-725. https://doi.org/10.1016/j.amjsurg.2008.11.043
Boughey, Judy C ; Goravanchi, Farzin ; Parris, Ronald N. ; Kee, Spencer S. ; Kowalski, Alicia M. ; Frenzel, John C. ; Bedrosian, Isabelle ; Meric-Bernstam, Funda ; Hunt, Kelly K. ; Ames, Frederick C. ; Kuerer, Henry M. ; Lucci, Anthony. / Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery. In: American Journal of Surgery. 2009 ; Vol. 198, No. 5. pp. 720-725.
@article{31d7a222d82a4b98a14d6b3a6fb1c552,
title = "Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery",
abstract = "Background: The goal of the current study was to evaluate the effect of regional anesthesia using paravertebral block (PVB) on postoperative pain after breast surgery. Methods: Patients undergoing unilateral breast surgery without reconstruction were randomized to general anesthesia (GA) only or PVB with GA and pain scores assessed. Results: Eighty patients were randomized (41 to GA and 39 to PVB with GA). Operative times were not significantly different between groups. Pain scores were lower after PVB compared to GA at 1 hour (1 vs 3, P = .006) and 3 hours (0 vs 2, P = .001) but not at later time points. The overall worst pain experienced was lower with PVB (3 vs 5, P = .02). More patients were pain-free in the PVB group at 1 hour (44{\%} vs 17{\%}, P = .014) and 3 hours (54{\%} vs 17{\%}, P = .005) postoperatively. Conclusions: PVB significantly decreases postoperative pain up to 3 hours after breast cancer surgery.",
keywords = "Breast surgery, Length of stay, Pain control, Paravertebral block, Postoperative pain, Regional anesthesia",
author = "Boughey, {Judy C} and Farzin Goravanchi and Parris, {Ronald N.} and Kee, {Spencer S.} and Kowalski, {Alicia M.} and Frenzel, {John C.} and Isabelle Bedrosian and Funda Meric-Bernstam and Hunt, {Kelly K.} and Ames, {Frederick C.} and Kuerer, {Henry M.} and Anthony Lucci",
year = "2009",
month = "11",
doi = "10.1016/j.amjsurg.2008.11.043",
language = "English (US)",
volume = "198",
pages = "720--725",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery

AU - Boughey, Judy C

AU - Goravanchi, Farzin

AU - Parris, Ronald N.

AU - Kee, Spencer S.

AU - Kowalski, Alicia M.

AU - Frenzel, John C.

AU - Bedrosian, Isabelle

AU - Meric-Bernstam, Funda

AU - Hunt, Kelly K.

AU - Ames, Frederick C.

AU - Kuerer, Henry M.

AU - Lucci, Anthony

PY - 2009/11

Y1 - 2009/11

N2 - Background: The goal of the current study was to evaluate the effect of regional anesthesia using paravertebral block (PVB) on postoperative pain after breast surgery. Methods: Patients undergoing unilateral breast surgery without reconstruction were randomized to general anesthesia (GA) only or PVB with GA and pain scores assessed. Results: Eighty patients were randomized (41 to GA and 39 to PVB with GA). Operative times were not significantly different between groups. Pain scores were lower after PVB compared to GA at 1 hour (1 vs 3, P = .006) and 3 hours (0 vs 2, P = .001) but not at later time points. The overall worst pain experienced was lower with PVB (3 vs 5, P = .02). More patients were pain-free in the PVB group at 1 hour (44% vs 17%, P = .014) and 3 hours (54% vs 17%, P = .005) postoperatively. Conclusions: PVB significantly decreases postoperative pain up to 3 hours after breast cancer surgery.

AB - Background: The goal of the current study was to evaluate the effect of regional anesthesia using paravertebral block (PVB) on postoperative pain after breast surgery. Methods: Patients undergoing unilateral breast surgery without reconstruction were randomized to general anesthesia (GA) only or PVB with GA and pain scores assessed. Results: Eighty patients were randomized (41 to GA and 39 to PVB with GA). Operative times were not significantly different between groups. Pain scores were lower after PVB compared to GA at 1 hour (1 vs 3, P = .006) and 3 hours (0 vs 2, P = .001) but not at later time points. The overall worst pain experienced was lower with PVB (3 vs 5, P = .02). More patients were pain-free in the PVB group at 1 hour (44% vs 17%, P = .014) and 3 hours (54% vs 17%, P = .005) postoperatively. Conclusions: PVB significantly decreases postoperative pain up to 3 hours after breast cancer surgery.

KW - Breast surgery

KW - Length of stay

KW - Pain control

KW - Paravertebral block

KW - Postoperative pain

KW - Regional anesthesia

UR - http://www.scopus.com/inward/record.url?scp=71749085846&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=71749085846&partnerID=8YFLogxK

U2 - 10.1016/j.amjsurg.2008.11.043

DO - 10.1016/j.amjsurg.2008.11.043

M3 - Article

C2 - 19427625

AN - SCOPUS:71749085846

VL - 198

SP - 720

EP - 725

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 5

ER -