Prophylactic surgery for women at high risk for breast cancer.

D. K. Blanchard, L. C. Hartmann

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Women at high risk for the development of breast cancer have several options open to them including increased cancer surveillance, prophylactic mastectomy and/or oophorectomy, and chemoprevention. We consider high-risk women to be those with known BRCA mutations or a strong family history characterized by multiple relatives with breast cancer, early age at diagnosis, and in some families, ovarian cancer. We present existing data regarding prophylactic surgery for these women. Essentially, a woman at high risk for breast cancer may choose to undergo bilateral prophylactic mastectomy, with or without reconstruction. For patients who have a known breast cancer, contralateral mastectomy is also an option. Finally, for women in families with a strong incidence of ovarian cancer, prophylactic oophorectomy can be considered.

Original languageEnglish (US)
Pages (from-to)127-134
Number of pages8
JournalClinical Breast Cancer
Volume1
Issue number2
StatePublished - Jul 2000

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Breast Neoplasms
Ovariectomy
Ovarian Neoplasms
Mastectomy
Chemoprevention
Mutation
Incidence
Neoplasms
Prophylactic Mastectomy

ASJC Scopus subject areas

  • Cancer Research

Cite this

Blanchard, D. K., & Hartmann, L. C. (2000). Prophylactic surgery for women at high risk for breast cancer. Clinical Breast Cancer, 1(2), 127-134.

Prophylactic surgery for women at high risk for breast cancer. / Blanchard, D. K.; Hartmann, L. C.

In: Clinical Breast Cancer, Vol. 1, No. 2, 07.2000, p. 127-134.

Research output: Contribution to journalArticle

Blanchard, DK & Hartmann, LC 2000, 'Prophylactic surgery for women at high risk for breast cancer.', Clinical Breast Cancer, vol. 1, no. 2, pp. 127-134.
Blanchard, D. K. ; Hartmann, L. C. / Prophylactic surgery for women at high risk for breast cancer. In: Clinical Breast Cancer. 2000 ; Vol. 1, No. 2. pp. 127-134.
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