Prokinetics in gastroparesis

Research output: Contribution to journalReview article

48 Scopus citations

Abstract

Prokinetic agents are medications that enhance coordinated gastrointestinal motility and transit of content in the gastrointestinal tract, mainly by amplifying and coordinating the gastrointestinal muscular contractions. In addition to dietary therapy, prokinetic therapy should be considered as a means to improve gastric emptying and symptoms of gastroparesis, balancing benefits and risks of treatment. In the United States, metoclopramide remains the first-line prokinetic therapy, because it is the only approved medication for gastroparesis. Newer agents are being developed for the management of gastroparesis. This article provides detailed information about prokinetic agents for the treatment of gastroparesis.

Original languageEnglish (US)
Pages (from-to)97-111
Number of pages15
JournalGastroenterology Clinics of North America
Volume44
Issue number1
DOIs
StatePublished - Mar 1 2015

Keywords

  • Domperidone
  • Erythromycin
  • Ghrelin
  • Metoclopramide
  • Pharmacology
  • Pyridostigmine
  • Receptor
  • Relamorelin
  • Serotonin

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Prokinetics in gastroparesis'. Together they form a unique fingerprint.

  • Cite this