Progressive supranuclear palsy phenotype secondary to CADASIL

J. A. Van Gerpen, J. E. Ahlskog, G. W. Petty

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Background and purpose. To report a unique case of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy manifesting as a progressive supranuclear palsy phenotype, thereby expanding its recognized presentations. Methods. Review of the pertinent literature from MEDLINE, cross-referencing cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, progressive supranuclear palsy, and parkinsonism. Description of a 60-year-old woman who presented with a several year history of step-wise, progressive parkinsonism secondary to cerebral autosomal dominant arteriopathy. Results. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy may present with a progressive supranuclear phenotype. Conclusion. Parkinsonism, including a progressive supranuclear palsy phenotype, is one of a growing number of recognized ways that cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy may present.

Original languageEnglish (US)
Pages (from-to)367-369
Number of pages3
JournalParkinsonism and Related Disorders
Volume9
Issue number6
DOIs
StatePublished - Aug 2003

Keywords

  • Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
  • Parkinsonism
  • Progressive supranuclear palsy (PSP)

ASJC Scopus subject areas

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Progressive supranuclear palsy phenotype secondary to CADASIL'. Together they form a unique fingerprint.

  • Cite this