Principles of Good Clinical Trial Design

Ming Wen An, Quyen Duong, Jennifer Le-Rademacher, Sumithra J Mandrekar

Research output: Contribution to journalArticle

Abstract

Clinical trials are a fundamental component of medical research and serve as the main route to obtain evidence of the safety and efficacy of treatment before its approval. A trial's ability to provide the intended evidence hinges on appropriate design, background knowledge, trial rationale to sample size, and interim monitoring rules. In this article, we present some general design principles for investigators and their research teams to consider when planning to conduct a trial.

Original languageEnglish (US)
Pages (from-to)1277-1280
Number of pages4
JournalJournal of Thoracic Oncology
Volume15
Issue number8
DOIs
StatePublished - Aug 2020

Keywords

  • Clinical trial
  • Collaboration
  • Design
  • Principles

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

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