Primary sclerosing cholangitis: Current and future management strategies

John E. Eaton; Jayant A. Talwalkar

doi:10.1007/s11901-012-0155-1

Primary sclerosing cholangitis: Current and future management strategies

John E. Eaton, Jayant A. Talwalkar

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease. The etiology of this disorder is unknown and there are no effective medical therapies. PSC is associated with inflammatory bowel disease and an increased risk for hepatobiliary and colorectal malignancies. The aim of this review is to highlight the clinical features and diagnostic approach to patients with suspected PSC, characterize associated comorbidities, review screening strategies for PSC associated malignancies and review contemporary and future therapies.

Original language	English (US)
Pages (from-to)	28-36
Number of pages	9
Journal	Current Hepatitis Reports
Volume	12
Issue number	1
DOIs	https://doi.org/10.1007/s11901-012-0155-1
State	Published - Mar 2013

Keywords

Diagnosis
Management
Primary sclerosing cholangitis

ASJC Scopus subject areas

Hepatology
Virology

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10.1007/s11901-012-0155-1

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title = "Primary sclerosing cholangitis: Current and future management strategies",

abstract = "Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease. The etiology of this disorder is unknown and there are no effective medical therapies. PSC is associated with inflammatory bowel disease and an increased risk for hepatobiliary and colorectal malignancies. The aim of this review is to highlight the clinical features and diagnostic approach to patients with suspected PSC, characterize associated comorbidities, review screening strategies for PSC associated malignancies and review contemporary and future therapies.",

keywords = "Diagnosis, Management, Primary sclerosing cholangitis",

author = "Eaton, {John E.} and Talwalkar, {Jayant A.}",

note = "Funding Information: Acknowledgements The authors are supported by NIH grant DK 56924.",

year = "2013",

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AU - Eaton, John E.

AU - Talwalkar, Jayant A.

N1 - Funding Information: Acknowledgements The authors are supported by NIH grant DK 56924.

PY - 2013/3

Y1 - 2013/3

N2 - Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease. The etiology of this disorder is unknown and there are no effective medical therapies. PSC is associated with inflammatory bowel disease and an increased risk for hepatobiliary and colorectal malignancies. The aim of this review is to highlight the clinical features and diagnostic approach to patients with suspected PSC, characterize associated comorbidities, review screening strategies for PSC associated malignancies and review contemporary and future therapies.

AB - Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease. The etiology of this disorder is unknown and there are no effective medical therapies. PSC is associated with inflammatory bowel disease and an increased risk for hepatobiliary and colorectal malignancies. The aim of this review is to highlight the clinical features and diagnostic approach to patients with suspected PSC, characterize associated comorbidities, review screening strategies for PSC associated malignancies and review contemporary and future therapies.

KW - Diagnosis

KW - Management

KW - Primary sclerosing cholangitis

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Primary sclerosing cholangitis: Current and future management strategies

Abstract

Keywords

ASJC Scopus subject areas

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