Primary amyloidosis (AL) in families

Morie Gertz, John P. Garton, Robert A. Kyle

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

We report the occurrence of immunoglobulin‐related amyloidosis (AL) in three separate families, each family having two members affected. None of the six patients had evidence to suggest the presence of familial amyloidosis (AF). Previously, immunoglobulin‐related amyloidosis (AL) was considered to be a sporadic disease process. Because of the occasional familial occurrence of other monoclonal gammopathies such as monoclonal gammopathy of undetermined significance, multiple myeloma, and macroglobulinemia of Waldenström, amyloidosis (AL) should be added to the list of immunopathies with a familial predisposition.

Original languageEnglish (US)
Pages (from-to)193-198
Number of pages6
JournalAmerican Journal of Hematology
Volume22
Issue number2
DOIs
StatePublished - Jan 1 1986

Keywords

  • amyloidosis (AL)
  • immunoglobulin‐related amyloidosis
  • monoclonal gammopathies
  • primary amyloidosis

ASJC Scopus subject areas

  • Hematology

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