Prenatal molecular genetic diagnosis of congenital long QT syndrome by strategic genotyping

David J. Tester, Jorge McCormack, Michael John Ackerman

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We demonstrate how genetic testing enabled a molecular prenatal diagnosis of congenital long QT syndrome in a 20-week fetus presenting with fetal bradycardia in the setting of maternal β-blocker therapy. Before prenatal testing, strategic genotyping, based on a family history of a near drowning, was performed on a 3-generation family with clinically diagnosed long QT syndrome in which the affected mother was pregnant.

Original languageEnglish (US)
Pages (from-to)788-791
Number of pages4
JournalAmerican Journal of Cardiology
Volume93
Issue number6
DOIs
StatePublished - Mar 15 2004

Fingerprint

Long QT Syndrome
Molecular Biology
Near Drowning
Genetic Testing
Bradycardia
Prenatal Diagnosis
Fetus
Mothers
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Prenatal molecular genetic diagnosis of congenital long QT syndrome by strategic genotyping. / Tester, David J.; McCormack, Jorge; Ackerman, Michael John.

In: American Journal of Cardiology, Vol. 93, No. 6, 15.03.2004, p. 788-791.

Research output: Contribution to journalArticle

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