Premotor symptoms and early diagnosis of Parkinson's disease

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Parkinson's disease is a disorder characterized by the motor findings of bradykinesia, rest tremor, cogwheel rigidity, and postural instability. As the disease progresses, most patients develop numerous nonmotor signs and symptoms, many of which play a major role in reducing quality of life. What is becoming increasingly clear is that nonmotor findings, including hyposmia, sleep disorders, autonomic abnormalities, cognitive changes, and neurobehavioral changes, often precede the motor findings.

Original languageEnglish (US)
Pages (from-to)3-8
Number of pages6
JournalInternational Journal of Neuroscience
Volume121
Issue numberSUPPL. 2
DOIs
StatePublished - Nov 30 2011

Keywords

  • Autonomic disorders
  • Cognitive impairment
  • Depression
  • Olfaction

ASJC Scopus subject areas

  • Neuroscience(all)

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