Preexisting atrial fibrillation and cardiac complications after liver transplantation

Johannes Bargehr, Jorge F. Trejo-Gutierrez, Tushar C Patel, Barry Rosser, Jaime Aranda-Michel, Maria Yataco, C. Burcin Taner

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with increased cardiovascular morbidity and all-cause mortality. Our aim was to determine the impact of preexisting AF on patients undergoing liver transplantation (LT). A retrospective case-control study was performed. Records from patients who underwent LT between January 2005 and December 2008 at Mayo Clinic Florida were reviewed. Patients with preexisting AF were identified and matched to patients who did not have a diagnosis of AF. Thirty-two of 717 LT recipients (4.5%) had AF before LT. These patients were compared to a control group of 63 LT recipients. Pre-LT left ventricular hypertrophy (P=0.03), a history of congestive heart failure (P=0.04), and a history of stroke or transient ischemic attack (P=0.03) were significantly more prevalent in patients with AF versus controls. Intraoperative adverse cardiac events (P=0.02) and AF-related adverse postoperative events (P<0.001) were more common in the recipients with known AF. Six patients with paroxysmal AF (19%) developed chronic/ persistent AF postoperatively. Graft survival and patient survival were similar in the groups. Although patients with AF had a higher incidence of intraoperative cardiac events, a higher cardiovascular morbidity rate, and a complicated postoperative course, this did not affect overall graft and patient survival.

Original languageEnglish (US)
Pages (from-to)314-320
Number of pages7
JournalLiver Transplantation
Volume21
Issue number3
DOIs
StatePublished - Mar 1 2015

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Liver Transplantation
Atrial Fibrillation
Graft Survival
Morbidity
Transient Ischemic Attack
Left Ventricular Hypertrophy
Case-Control Studies
Cardiac Arrhythmias
Heart Failure
Stroke
Control Groups
Survival
Mortality
Incidence

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Hepatology

Cite this

Bargehr, J., Trejo-Gutierrez, J. F., Patel, T. C., Rosser, B., Aranda-Michel, J., Yataco, M., & Taner, C. B. (2015). Preexisting atrial fibrillation and cardiac complications after liver transplantation. Liver Transplantation, 21(3), 314-320. https://doi.org/10.1002/lt.24060

Preexisting atrial fibrillation and cardiac complications after liver transplantation. / Bargehr, Johannes; Trejo-Gutierrez, Jorge F.; Patel, Tushar C; Rosser, Barry; Aranda-Michel, Jaime; Yataco, Maria; Taner, C. Burcin.

In: Liver Transplantation, Vol. 21, No. 3, 01.03.2015, p. 314-320.

Research output: Contribution to journalArticle

Bargehr, J, Trejo-Gutierrez, JF, Patel, TC, Rosser, B, Aranda-Michel, J, Yataco, M & Taner, CB 2015, 'Preexisting atrial fibrillation and cardiac complications after liver transplantation', Liver Transplantation, vol. 21, no. 3, pp. 314-320. https://doi.org/10.1002/lt.24060
Bargehr, Johannes ; Trejo-Gutierrez, Jorge F. ; Patel, Tushar C ; Rosser, Barry ; Aranda-Michel, Jaime ; Yataco, Maria ; Taner, C. Burcin. / Preexisting atrial fibrillation and cardiac complications after liver transplantation. In: Liver Transplantation. 2015 ; Vol. 21, No. 3. pp. 314-320.
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