Predicting Cognitive Impairment in Epilepsy: Findings from the Bozeman Epilepsy Consortium

Esther Strauss, David Loring, Gordon Chelune, Michael Hunter, Bruce Hermann, K. Kenneth, Michael Westerveld, Max Trenerry, William Barr

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93 Scopus citations

Abstract

We examined the contribution of age of seizure onset, seizure duration, seizure laterality, seizure location, gender, handedness, and cerebral speech representation to cognitive attainment in 1,141 patients with medically refractory seizures. The combined influence of the predictor variables was modest. Age of seizure onset was the best single indicator of Full Scale IQ (partial r -. 23) and General Memory (partial r =. 20). Laterality and location of dysfunction, and cerebral speech dominance were also relevant and independent indicators of aspects of cognition. Except for age of onset of seizures (early onset was associated with poorer cognitive attainment), however, the magnitude of the effects was limited.

Original languageEnglish (US)
Pages (from-to)909-917
Number of pages9
JournalJournal of Clinical and Experimental Neuropsychology
Volume17
Issue number6
DOIs
StatePublished - Dec 1 1995

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ASJC Scopus subject areas

  • Clinical Psychology
  • Neurology
  • Clinical Neurology

Cite this

Strauss, E., Loring, D., Chelune, G., Hunter, M., Hermann, B., Kenneth, K., Westerveld, M., Trenerry, M., & Barr, W. (1995). Predicting Cognitive Impairment in Epilepsy: Findings from the Bozeman Epilepsy Consortium. Journal of Clinical and Experimental Neuropsychology, 17(6), 909-917. https://doi.org/10.1080/01688639508402439