Potential applications of gene therapy in sports medicine

C. H. Evans, S. C. Ghivizzani, P. D. Robbins

Research output: Contribution to journalReview article

4 Scopus citations

Abstract

Gene therapy has the potential to improve greatly the management of sports medicine injuries. By the expeditious introduction of the appropriate genes to sites of injury, it should prove possible to initiate healing responses in those tissues that normally fail to heal, to accelerate healing in tissues which do naturally heal, and to improve the quality of the repair tissue. In addition, genes with anti-inflammatory properties offer novel possibilities for the control of chronic, sports related inflammation. None of these applications of gene therapy in sports medicine is yet in the clinic. It would seem, however, only a matter of time before the first clinical trials emerge. Their acceptance will be facilitated by the two human protocols that are presently underway for the treatment of rheumatoid arthritis. The present status of sports medicine gene therapy is summarized in Table 3.

Original languageEnglish (US)
Pages (from-to)405-416
Number of pages12
JournalPhysical Medicine and Rehabilitation Clinics of North America
Volume11
Issue number2
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

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