Portal vein thrombosis

Hector Rodriguez-Luna, Hugo E. Vargas

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

Portal vein thrombosis (PVT) can be a difficult clinical problem to assess and manage. A high index of suspicion is needed for a PVT diagnosis given the subtle presentation and potentially serious long-term complications. It should be considered a clue to the presence of one or several underlying disorders, including prothrombotic disorders, whether or not a local precipitating factor is identified. The accruing evidence shows that acute PVT can and probably should be treated with anticoagulation or thrombolytic agents in an effort to prevent extension of thrombus, mesenteric vessel occlusion, and portal hypertension. However, chronic PVT should be treated conservatively with measures to control major consequences related to portal hypertension. Anticoagulation therapy duration should be tailored to the identified predisposing factors.

Original languageEnglish (US)
Pages (from-to)435-443
Number of pages9
JournalCurrent Treatment Options in Gastroenterology
Volume10
Issue number6
DOIs
StatePublished - Dec 1 2007

ASJC Scopus subject areas

  • Gastroenterology

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