Porous silicon-based scaffolds for tissue engineering and other biomedical applications

Jeffery L. Coffer, Melanie A. Whitehead, Dattatri K. Nagesha, Priyabrata Mukherjee, Giridhar Akkaraju, Mihaela Totolici, Roghieh S. Saffie, Leigh T. Canham

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

This work describes the formation of porous composite materials based on a combination of bioactive mesoporous silicon and bioerodible polymers such as poly-caprolactone (PCL). The fabrication of a range of composites prepared by both salt leaching and microemulsion techniques are discussed. Particular attention to the influence of Si content in the composite on in vitro calcification assays are assessed. For each system, cytotoxicity and cellular proliferation are explicitly evaluated through fibroblast cell culture assays.

Original languageEnglish (US)
Pages (from-to)1451-1455
Number of pages5
JournalPhysica Status Solidi (A) Applications and Materials Science
Volume202
Issue number8
DOIs
StatePublished - Jun 2005
Externally publishedYes

Fingerprint

tissue engineering
Porous silicon
Scaffolds (biology)
porous silicon
Tissue engineering
composite materials
Assays
Composite materials
silicon polymers
calcification
Microemulsions
fibroblasts
Silicon
leaching
Fibroblasts
Cytotoxicity
activity (biology)
Cell culture
Leaching
Porous materials

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Coffer, J. L., Whitehead, M. A., Nagesha, D. K., Mukherjee, P., Akkaraju, G., Totolici, M., ... Canham, L. T. (2005). Porous silicon-based scaffolds for tissue engineering and other biomedical applications. Physica Status Solidi (A) Applications and Materials Science, 202(8), 1451-1455. https://doi.org/10.1002/pssa.200461134

Porous silicon-based scaffolds for tissue engineering and other biomedical applications. / Coffer, Jeffery L.; Whitehead, Melanie A.; Nagesha, Dattatri K.; Mukherjee, Priyabrata; Akkaraju, Giridhar; Totolici, Mihaela; Saffie, Roghieh S.; Canham, Leigh T.

In: Physica Status Solidi (A) Applications and Materials Science, Vol. 202, No. 8, 06.2005, p. 1451-1455.

Research output: Contribution to journalArticle

Coffer, JL, Whitehead, MA, Nagesha, DK, Mukherjee, P, Akkaraju, G, Totolici, M, Saffie, RS & Canham, LT 2005, 'Porous silicon-based scaffolds for tissue engineering and other biomedical applications', Physica Status Solidi (A) Applications and Materials Science, vol. 202, no. 8, pp. 1451-1455. https://doi.org/10.1002/pssa.200461134
Coffer, Jeffery L. ; Whitehead, Melanie A. ; Nagesha, Dattatri K. ; Mukherjee, Priyabrata ; Akkaraju, Giridhar ; Totolici, Mihaela ; Saffie, Roghieh S. ; Canham, Leigh T. / Porous silicon-based scaffolds for tissue engineering and other biomedical applications. In: Physica Status Solidi (A) Applications and Materials Science. 2005 ; Vol. 202, No. 8. pp. 1451-1455.
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