Pneumotaxic area neuronal discharge during sleep-waking states in the cat

Gary C. Sieck; Ronald M. Harper

doi:10.1016/0014-4886(80)90162-4

Pneumotaxic area neuronal discharge during sleep-waking states in the cat

Gary C. Sieck, Ronald M. Harper

Physiology & Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

We examined the spontaneous activity of single neurons within the nucleus parabrachialis medialis (NPBM; pneumotaxic center) of unanesthetized, unrestrained cats in relation to the respiratory cycle during different sleep-waking states. State-related changes were found in the mean discharge rate of NPBM neurons and in the relationship of their activity to the respiratory cycle. These changes in pneumotaxic center neuronal activity paralleled the variations in respiratory patterns associated with different sleep-waking states. State-related changes in NPBM neuronal activity could partially account for the different respiratory patterns of each sleep-waking state by modulating inspiratory-expiratory phase transitions.

Original language	English (US)
Pages (from-to)	79-102
Number of pages	24
Journal	Experimental Neurology
Volume	67
Issue number	1
DOIs	https://doi.org/10.1016/0014-4886(80)90162-4
State	Published - Jan 1980

ASJC Scopus subject areas

Neurology
Developmental Neuroscience

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10.1016/0014-4886(80)90162-4

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@article{d725671421464326a3736a7c2ff646c0,

title = "Pneumotaxic area neuronal discharge during sleep-waking states in the cat",

abstract = "We examined the spontaneous activity of single neurons within the nucleus parabrachialis medialis (NPBM; pneumotaxic center) of unanesthetized, unrestrained cats in relation to the respiratory cycle during different sleep-waking states. State-related changes were found in the mean discharge rate of NPBM neurons and in the relationship of their activity to the respiratory cycle. These changes in pneumotaxic center neuronal activity paralleled the variations in respiratory patterns associated with different sleep-waking states. State-related changes in NPBM neuronal activity could partially account for the different respiratory patterns of each sleep-waking state by modulating inspiratory-expiratory phase transitions.",

author = "Sieck, {Gary C.} and Harper, {Ronald M.}",

note = "Funding Information: Abbreviations: NPBM-nucleus parabrachialis medialis, AW-awake, QS-quiet sleep, REM-rapid eye movement, CNS-central nervous system, EEG-electroencephalogram. EMG-electromyogram. {\textquoteright} The authors wish to thank S. Glotzback. S. Frankmann, and B. Truex for their invaluable assistance in this study. This research was supported by grant ROI HL-22418-01 from the National Institutes of Health and by U.S. Public Health Service Research Fellowship award NS05349-03 to G.C.S.",

year = "1980",

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doi = "10.1016/0014-4886(80)90162-4",

language = "English (US)",

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journal = "Experimental Neurology",

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T1 - Pneumotaxic area neuronal discharge during sleep-waking states in the cat

AU - Sieck, Gary C.

AU - Harper, Ronald M.

N1 - Funding Information: Abbreviations: NPBM-nucleus parabrachialis medialis, AW-awake, QS-quiet sleep, REM-rapid eye movement, CNS-central nervous system, EEG-electroencephalogram. EMG-electromyogram. ’ The authors wish to thank S. Glotzback. S. Frankmann, and B. Truex for their invaluable assistance in this study. This research was supported by grant ROI HL-22418-01 from the National Institutes of Health and by U.S. Public Health Service Research Fellowship award NS05349-03 to G.C.S.

PY - 1980/1

Y1 - 1980/1

N2 - We examined the spontaneous activity of single neurons within the nucleus parabrachialis medialis (NPBM; pneumotaxic center) of unanesthetized, unrestrained cats in relation to the respiratory cycle during different sleep-waking states. State-related changes were found in the mean discharge rate of NPBM neurons and in the relationship of their activity to the respiratory cycle. These changes in pneumotaxic center neuronal activity paralleled the variations in respiratory patterns associated with different sleep-waking states. State-related changes in NPBM neuronal activity could partially account for the different respiratory patterns of each sleep-waking state by modulating inspiratory-expiratory phase transitions.

AB - We examined the spontaneous activity of single neurons within the nucleus parabrachialis medialis (NPBM; pneumotaxic center) of unanesthetized, unrestrained cats in relation to the respiratory cycle during different sleep-waking states. State-related changes were found in the mean discharge rate of NPBM neurons and in the relationship of their activity to the respiratory cycle. These changes in pneumotaxic center neuronal activity paralleled the variations in respiratory patterns associated with different sleep-waking states. State-related changes in NPBM neuronal activity could partially account for the different respiratory patterns of each sleep-waking state by modulating inspiratory-expiratory phase transitions.

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Pneumotaxic area neuronal discharge during sleep-waking states in the cat

Abstract

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