Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment.

Antoine Lesuffleur; Kwan Seop Lim; Nathan C. Lindquist; Hyungsoon Im; Arthur E. Warrington; Moses Rodriguez; Sang Hyun Oh

Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment.

Antoine Lesuffleur, Kwan Seop Lim, Nathan C. Lindquist, Hyungsoon Im, Arthur E. Warrington, Moses Rodriguez, Sang Hyun Oh

Research output: Contribution to journal › Article › peer-review

Abstract

We integrate periodic nanohole arrays in a thin gold film with lipid membranes in a microfluidic channel. Surface plasmon-enhanced light transmission through the periodic nanohole arrays enables real-time label-free sensing of molecular binding on the lipid membrane surface. This membrane biosensor can potentially act as a natural platform for studying binding kinetics of proteins with their binding partners anchored in the lipid membrane. We also present the concept of using nanopore arrays for kinetic assays of transmembrane proteins in a free-standing lipid membrane.

Original language	English (US)
Pages (from-to)	1481-1484
Number of pages	4
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
State	Published - 2009
Externally published	Yes

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

Cite this

Lesuffleur, A., Lim, K. S., Lindquist, N. C., Im, H., Warrington, A. E., Rodriguez, M., & Oh, S. H. (2009). Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 1481-1484.

Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment. / Lesuffleur, Antoine; Lim, Kwan Seop; Lindquist, Nathan C. et al.
In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2009, p. 1481-1484.

Research output: Contribution to journal › Article › peer-review

Lesuffleur, A, Lim, KS, Lindquist, NC, Im, H, Warrington, AE, Rodriguez, M & Oh, SH 2009, 'Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 1481-1484.

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AU - Warrington, Arthur E.

AU - Rodriguez, Moses

AU - Oh, Sang Hyun

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Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment.

Abstract

ASJC Scopus subject areas

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