Personalized pharmacotherapy for Type 2 diabetes mellitus

Airani Sathananthan, Adrian Vella

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Genome-wide linkage and association studies have been applied to Type 2 diabetes in order to discover common genetic variation that contributes to disease risk. While there has been progress in understanding how genetic variation predisposes to diabetes, there is less of an understanding of how genetics can alter drug response. The hope is that in the future, pharmacogenetics can help guide the treatment of diabetes, thereby improving control while minimizing side effects in a large group of patients.

Original languageEnglish (US)
Pages (from-to)417-422
Number of pages6
JournalPersonalized Medicine
Volume6
Issue number4
DOIs
StatePublished - 2009

Keywords

  • OCT 1
  • Pharmacogenetics
  • Sulfonylureas
  • TCF7L2
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology

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