Periportal sinusoidal dilatation, inflammatory bowel disease, and the contraceptive pill

Michael Camilleri; Katherine Schafler; Vinton S. Chadwick; Humphrey J. Hodgson; Kenneth Weinbren

doi:10.1016/0016-5085(81)90145-1

Periportal sinusoidal dilatation, inflammatory bowel disease, and the contraceptive pill

Michael Camilleri, Katherine Schafler, Vinton S. Chadwick, Humphrey J. Hodgson, Kenneth Weinbren

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Two women, aged 19 and 28 yr, who had been on the contraceptive pill for at least 18 mo, developed abnormal levels of circulating liver enzymes, minimal hepatomegaly, and elevated erythrocyte sedimentation rate. Liver biopsy in both women showed a sinusoidal dilatation sparing the perihepatic venous regions. The liver function abnormality resolved on stopping the pill. Both patients also had clinically mild inflammatory bowel disease. The possibility of both liver and bowel abnormalities being effects of contraceptive steroids is discussed.

Original language	English (US)
Pages (from-to)	810-815
Number of pages	6
Journal	Gastroenterology
Volume	80
Issue number	4
DOIs	https://doi.org/10.1016/0016-5085(81)90145-1
State	Published - Apr 1981

ASJC Scopus subject areas

Hepatology
Gastroenterology

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abstract = "Two women, aged 19 and 28 yr, who had been on the contraceptive pill for at least 18 mo, developed abnormal levels of circulating liver enzymes, minimal hepatomegaly, and elevated erythrocyte sedimentation rate. Liver biopsy in both women showed a sinusoidal dilatation sparing the perihepatic venous regions. The liver function abnormality resolved on stopping the pill. Both patients also had clinically mild inflammatory bowel disease. The possibility of both liver and bowel abnormalities being effects of contraceptive steroids is discussed.",

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AU - Camilleri, Michael

AU - Schafler, Katherine

AU - Chadwick, Vinton S.

AU - Hodgson, Humphrey J.

AU - Weinbren, Kenneth

PY - 1981/4

Y1 - 1981/4

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AB - Two women, aged 19 and 28 yr, who had been on the contraceptive pill for at least 18 mo, developed abnormal levels of circulating liver enzymes, minimal hepatomegaly, and elevated erythrocyte sedimentation rate. Liver biopsy in both women showed a sinusoidal dilatation sparing the perihepatic venous regions. The liver function abnormality resolved on stopping the pill. Both patients also had clinically mild inflammatory bowel disease. The possibility of both liver and bowel abnormalities being effects of contraceptive steroids is discussed.

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Periportal sinusoidal dilatation, inflammatory bowel disease, and the contraceptive pill

Abstract

ASJC Scopus subject areas

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