Abstract
Peripheral T-cell lymphomas (PTCLs) are malignancies of immunologically mature T-cells that arise in peripheral lymphoid tissues such as lymph nodes, spleen, gastrointestinal tract, and skin. These lymphomas are uncommon as compared with the incidence of B-cell lymphomas, and they comprise only 5% to 10% of non-Hodgkin lymphomas in North America and Western Europe. A variety of specific disease entities have been recognized among PTCLs, and they tend to have lymph node, extranodal/cutaneous, or mixed leukemic/lymphomatous presentations. Most PTCLs have an aggressive clinical course. The clinicopathologic features of the various PTCLs are described herein.
Original language | English (US) |
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Pages (from-to) | 829-842 |
Number of pages | 14 |
Journal | Hematology/Oncology Clinics of North America |
Volume | 23 |
Issue number | 4 |
DOIs | |
State | Published - Aug 2009 |
Keywords
- Anaplastic large cell
- Angioimmunoblastic
- Enteropathy-associated
- HTLV-1
- Hepatosplenic
- Mycosis fungoides
- Peripheral T-cell lymphoma
ASJC Scopus subject areas
- Hematology
- Oncology