Perioperative management in total knee arthroplasty: Patient selection, pain management, thromboprophylaxis, and rehabilitation

Derek F. Amanatullah, Graham D. Pallante, Brian P. Chalmers, Mark Pagnano, Rafael J. Sierra

Research output: Contribution to journalArticle

4 Scopus citations


Optimization of patient expectations in TKA requires understanding the risk profile of each patient and tailoring preoperative counseling appropriately. There are numerous postoperative thromboprophylaxis regimens, but aspirin has gained consensus approval from the American Academy of Orthopaedic Surgeons and American College of Chest Physicians and may decrease the risk of bleeding when compared to other agents. Early mobilization or mechanical compression remain useful adjuncts to chemical thromboprophylaxis. Pre-emptive multimodal pain control is effective and minimizes narcotic-related side effects. Regional blockade and periarticular injection are effective strategies for site-specific pain control and avoid opioid induced side effects. Strategies for perioperative physical therapy vary widely and there are no well-defined guidelines for postoperative rehabilitation. Rehabilitation lacks durable clinical benefits long-term for the average patient. However, targeted utilization of perioperative rehabilitation to the most debilitated patients may be beneficial.

Original languageEnglish (US)
Pages (from-to)217-223
Number of pages7
JournalCurrent Orthopaedic Practice
Issue number3
StatePublished - Dec 1 2015



  • expectations
  • pain management
  • physical therapy
  • rehabilitation
  • thromboprophylaxis
  • Total knee arthroplasty

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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