Perineural tumor spread of bladder cancer causing lumbosacral plexopathy: an anatomic explanation

Daniel M. Aghion, Stepan Capek, Benjamin M. Howe, Jaroslaw T. Hepel, Sundaresan Sambandam, Adeotounbo A. Oyelese, Robert J. Spinner

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We present two cases of biopsy-proven neoplastic lumbosacral plexopathy from perineural spread of bladder cancer: one patient presented with predominantly sciatic nerve involvement and the second predominantly with obturator nerve involvement. These two patterns of perineural spread from bladder cancer were supported by imaging in our cases and solidified by review of the literature. Based on the innervation of the bladder, we provide an anatomic explanation for this observation. To our best knowledge, such an anatomic, mechanistic basis for perineural tumor spread in bladder cancer has not yet been described.

Original languageEnglish (US)
Pages (from-to)2331-2336
Number of pages6
JournalActa Neurochirurgica
Volume156
Issue number12
DOIs
StatePublished - Nov 16 2014

Fingerprint

Urinary Bladder Neoplasms
Obturator Nerve
Neoplasms
Sciatic Nerve
Urinary Bladder
Biopsy

Keywords

  • Bladder cancer
  • Lumbosacral plexopathy
  • Obturator neuropathy
  • Perineural tumor spread
  • Sciatic neuropathy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Aghion, D. M., Capek, S., Howe, B. M., Hepel, J. T., Sambandam, S., Oyelese, A. A., & Spinner, R. J. (2014). Perineural tumor spread of bladder cancer causing lumbosacral plexopathy: an anatomic explanation. Acta Neurochirurgica, 156(12), 2331-2336. https://doi.org/10.1007/s00701-014-2257-8

Perineural tumor spread of bladder cancer causing lumbosacral plexopathy : an anatomic explanation. / Aghion, Daniel M.; Capek, Stepan; Howe, Benjamin M.; Hepel, Jaroslaw T.; Sambandam, Sundaresan; Oyelese, Adeotounbo A.; Spinner, Robert J.

In: Acta Neurochirurgica, Vol. 156, No. 12, 16.11.2014, p. 2331-2336.

Research output: Contribution to journalArticle

Aghion, DM, Capek, S, Howe, BM, Hepel, JT, Sambandam, S, Oyelese, AA & Spinner, RJ 2014, 'Perineural tumor spread of bladder cancer causing lumbosacral plexopathy: an anatomic explanation', Acta Neurochirurgica, vol. 156, no. 12, pp. 2331-2336. https://doi.org/10.1007/s00701-014-2257-8
Aghion, Daniel M. ; Capek, Stepan ; Howe, Benjamin M. ; Hepel, Jaroslaw T. ; Sambandam, Sundaresan ; Oyelese, Adeotounbo A. ; Spinner, Robert J. / Perineural tumor spread of bladder cancer causing lumbosacral plexopathy : an anatomic explanation. In: Acta Neurochirurgica. 2014 ; Vol. 156, No. 12. pp. 2331-2336.
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