Abstract
We present two cases of biopsy-proven neoplastic lumbosacral plexopathy from perineural spread of bladder cancer: one patient presented with predominantly sciatic nerve involvement and the second predominantly with obturator nerve involvement. These two patterns of perineural spread from bladder cancer were supported by imaging in our cases and solidified by review of the literature. Based on the innervation of the bladder, we provide an anatomic explanation for this observation. To our best knowledge, such an anatomic, mechanistic basis for perineural tumor spread in bladder cancer has not yet been described.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2331-2336 |
| Number of pages | 6 |
| Journal | Acta Neurochirurgica |
| Volume | 156 |
| Issue number | 12 |
| DOIs | |
| State | Published - Nov 16 2014 |
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Keywords
- Bladder cancer
- Lumbosacral plexopathy
- Obturator neuropathy
- Perineural tumor spread
- Sciatic neuropathy
ASJC Scopus subject areas
- Surgery
- Clinical Neurology
Cite this
Perineural tumor spread of bladder cancer causing lumbosacral plexopathy : an anatomic explanation. / Aghion, Daniel M.; Capek, Stepan; Howe, Benjamin M.; Hepel, Jaroslaw T.; Sambandam, Sundaresan; Oyelese, Adeotounbo A.; Spinner, Robert J.
In: Acta Neurochirurgica, Vol. 156, No. 12, 16.11.2014, p. 2331-2336.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Perineural tumor spread of bladder cancer causing lumbosacral plexopathy
T2 - an anatomic explanation
AU - Aghion, Daniel M.
AU - Capek, Stepan
AU - Howe, Benjamin M.
AU - Hepel, Jaroslaw T.
AU - Sambandam, Sundaresan
AU - Oyelese, Adeotounbo A.
AU - Spinner, Robert J.
PY - 2014/11/16
Y1 - 2014/11/16
N2 - We present two cases of biopsy-proven neoplastic lumbosacral plexopathy from perineural spread of bladder cancer: one patient presented with predominantly sciatic nerve involvement and the second predominantly with obturator nerve involvement. These two patterns of perineural spread from bladder cancer were supported by imaging in our cases and solidified by review of the literature. Based on the innervation of the bladder, we provide an anatomic explanation for this observation. To our best knowledge, such an anatomic, mechanistic basis for perineural tumor spread in bladder cancer has not yet been described.
AB - We present two cases of biopsy-proven neoplastic lumbosacral plexopathy from perineural spread of bladder cancer: one patient presented with predominantly sciatic nerve involvement and the second predominantly with obturator nerve involvement. These two patterns of perineural spread from bladder cancer were supported by imaging in our cases and solidified by review of the literature. Based on the innervation of the bladder, we provide an anatomic explanation for this observation. To our best knowledge, such an anatomic, mechanistic basis for perineural tumor spread in bladder cancer has not yet been described.
KW - Bladder cancer
KW - Lumbosacral plexopathy
KW - Obturator neuropathy
KW - Perineural tumor spread
KW - Sciatic neuropathy
UR - http://www.scopus.com/inward/record.url?scp=84922096862&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84922096862&partnerID=8YFLogxK
U2 - 10.1007/s00701-014-2257-8
DO - 10.1007/s00701-014-2257-8
M3 - Article
C2 - 25338118
AN - SCOPUS:84922096862
VL - 156
SP - 2331
EP - 2336
JO - Acta Neurochirurgica
JF - Acta Neurochirurgica
SN - 0001-6268
IS - 12
ER -