TY - JOUR
T1 - Perineural tumor spread of bladder cancer causing lumbosacral plexopathy
T2 - an anatomic explanation
AU - Aghion, Daniel M.
AU - Capek, Stepan
AU - Howe, Benjamin M.
AU - Hepel, Jaroslaw T.
AU - Sambandam, Sundaresan
AU - Oyelese, Adeotounbo A.
AU - Spinner, Robert J.
N1 - Funding Information:
S.C. is supported by European Regional Development Fund - Project FNUSA-ICRC (No. CZ.1.05/1.1.00/02.0123)
Funding Information:
S.C. is supported by European Regional Development Fund - Project FNUSA-ICRC (No. CZ.1.05/1.1.00/02.0123).
Publisher Copyright:
© 2014, Springer-Verlag Wien.
PY - 2014/11/16
Y1 - 2014/11/16
N2 - We present two cases of biopsy-proven neoplastic lumbosacral plexopathy from perineural spread of bladder cancer: one patient presented with predominantly sciatic nerve involvement and the second predominantly with obturator nerve involvement. These two patterns of perineural spread from bladder cancer were supported by imaging in our cases and solidified by review of the literature. Based on the innervation of the bladder, we provide an anatomic explanation for this observation. To our best knowledge, such an anatomic, mechanistic basis for perineural tumor spread in bladder cancer has not yet been described.
AB - We present two cases of biopsy-proven neoplastic lumbosacral plexopathy from perineural spread of bladder cancer: one patient presented with predominantly sciatic nerve involvement and the second predominantly with obturator nerve involvement. These two patterns of perineural spread from bladder cancer were supported by imaging in our cases and solidified by review of the literature. Based on the innervation of the bladder, we provide an anatomic explanation for this observation. To our best knowledge, such an anatomic, mechanistic basis for perineural tumor spread in bladder cancer has not yet been described.
KW - Bladder cancer
KW - Lumbosacral plexopathy
KW - Obturator neuropathy
KW - Perineural tumor spread
KW - Sciatic neuropathy
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U2 - 10.1007/s00701-014-2257-8
DO - 10.1007/s00701-014-2257-8
M3 - Article
C2 - 25338118
AN - SCOPUS:84922096862
VL - 156
SP - 2331
EP - 2336
JO - Acta Neurochirurgica
JF - Acta Neurochirurgica
SN - 0001-6268
IS - 12
ER -