Abstract
A review of the pathophysiology of variceal bleeding, with a discussion of the pathogenesis of portal hypertension, formation of varices, and bleeding from varices. Portal hypertension results from increases in portal flow and portal vascular resistance. The factors increasing portal blood flow are primarily humoral. Resistance to portal flow has fixed and variable components. Elevated portal pressure leads to variceal formation. Variceal bleeding is dependent on portal pressure, variceal size, and variceal wall thickness.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 167-174 |
| Number of pages | 8 |
| Journal | Gastrointestinal Endoscopy Clinics of North America |
| Volume | 9 |
| Issue number | 2 |
| State | Published - 1999 |
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ASJC Scopus subject areas
- Surgery
- Gastroenterology
Cite this
Pathophysiology of variceal bleeding. / Roberts, Lewis Rowland; Kamath, Patrick Sequeira.
In: Gastrointestinal Endoscopy Clinics of North America, Vol. 9, No. 2, 1999, p. 167-174.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pathophysiology of variceal bleeding
AU - Roberts, Lewis Rowland
AU - Kamath, Patrick Sequeira
PY - 1999
Y1 - 1999
N2 - A review of the pathophysiology of variceal bleeding, with a discussion of the pathogenesis of portal hypertension, formation of varices, and bleeding from varices. Portal hypertension results from increases in portal flow and portal vascular resistance. The factors increasing portal blood flow are primarily humoral. Resistance to portal flow has fixed and variable components. Elevated portal pressure leads to variceal formation. Variceal bleeding is dependent on portal pressure, variceal size, and variceal wall thickness.
AB - A review of the pathophysiology of variceal bleeding, with a discussion of the pathogenesis of portal hypertension, formation of varices, and bleeding from varices. Portal hypertension results from increases in portal flow and portal vascular resistance. The factors increasing portal blood flow are primarily humoral. Resistance to portal flow has fixed and variable components. Elevated portal pressure leads to variceal formation. Variceal bleeding is dependent on portal pressure, variceal size, and variceal wall thickness.
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UR - http://www.scopus.com/inward/citedby.url?scp=0033046445&partnerID=8YFLogxK
M3 - Article
VL - 9
SP - 167
EP - 174
JO - Gastrointestinal Endoscopy Clinics of North America
JF - Gastrointestinal Endoscopy Clinics of North America
SN - 1052-5157
IS - 2
ER -