Open lung biopsy does not correlate with pulmonary function after the adult respiratory distress syndrome

M. R. Suchyta, C. G. Elliott, T. Colby, B. Y. Rasmusson, A. H. Morris, R. L. Jensen

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Abnormalities of pulmonary function occur following the adult respiratory distress syndrome (ARDS). To determine if open lung biopsy (OLB) during ARDS predicts late pulmonary function abnormalities, we examined nine survivors of ARDS who had OLB during ARDS. Open lung biopsy was performed within two weeks of the diagnosis of ARDS, and the following were scored by a pulmonary pathologist as to extent and severity: hyaline membranes (HM), interstitial fibrosis (IF), air space organization (AO), interstitial cellularity (IC), and type 2 cell proliferation (T2C). Pulmonary function tests performed at least one year after ARDS were also used for analysis. Percent predicted D(CO), TLC, DL/VA, and FVC were regressed against extent, severity, and combined scores. No significant correlation was found despite impressive histologic abnormalities. These data suggest that the severity and extent of HM, IF, AO, T2C, or IC do not correlate with lung function following ARDS.

Original languageEnglish (US)
Pages (from-to)1232-1237
Number of pages6
JournalChest
Volume99
Issue number5
StatePublished - 1991
Externally publishedYes

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Adult Respiratory Distress Syndrome
Biopsy
Lung
Hyalin
Fibrosis
Air
Cell Proliferation
Membranes
Respiratory Function Tests
Carbon Monoxide

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Suchyta, M. R., Elliott, C. G., Colby, T., Rasmusson, B. Y., Morris, A. H., & Jensen, R. L. (1991). Open lung biopsy does not correlate with pulmonary function after the adult respiratory distress syndrome. Chest, 99(5), 1232-1237.

Open lung biopsy does not correlate with pulmonary function after the adult respiratory distress syndrome. / Suchyta, M. R.; Elliott, C. G.; Colby, T.; Rasmusson, B. Y.; Morris, A. H.; Jensen, R. L.

In: Chest, Vol. 99, No. 5, 1991, p. 1232-1237.

Research output: Contribution to journalArticle

Suchyta, MR, Elliott, CG, Colby, T, Rasmusson, BY, Morris, AH & Jensen, RL 1991, 'Open lung biopsy does not correlate with pulmonary function after the adult respiratory distress syndrome', Chest, vol. 99, no. 5, pp. 1232-1237.
Suchyta MR, Elliott CG, Colby T, Rasmusson BY, Morris AH, Jensen RL. Open lung biopsy does not correlate with pulmonary function after the adult respiratory distress syndrome. Chest. 1991;99(5):1232-1237.
Suchyta, M. R. ; Elliott, C. G. ; Colby, T. ; Rasmusson, B. Y. ; Morris, A. H. ; Jensen, R. L. / Open lung biopsy does not correlate with pulmonary function after the adult respiratory distress syndrome. In: Chest. 1991 ; Vol. 99, No. 5. pp. 1232-1237.
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